Evidence map›Paper›PMID 27682330›Full record

SynthesisThorax2017

Socio-economic inequalities in stage at diagnosis, and in time intervals on the lung cancer pathway from first symptom to treatment: systematic review and meta-analysis.

Lynne F Forrest, Sarah Sowden, Greg Rubin, Martin White, Jean Adams

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Thorax, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Guideline
  2. Pooled it
  3. Socioeconomic Disadvantage and Care Proximity Influence Stage at Presentation in Head and Neck Cancer.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2026
    Article
  4. Article
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  8. Review
  9. Article
  10. Article
  11. Smoking, Lung Cancer Stage, and Prognostic Factors-Findings from the National Lung Screening Trial.International journal of environmental research and public health · 2024
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Work-Related Factors and Lung Cancer Survival: A Population-Based Study in Switzerland (1990-2014).International journal of environmental research and public health · 2022
    Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Lynne F ForrestInstitute of Health & Society, Newcastle University, Newcastle upon Tyne, UK.ORCID 0000-0002-3740-5541
Sarah SowdenInstitute of Health & Society, Newcastle University, Newcastle upon Tyne, UK.
Greg RubinFuse, UKCRC Centre for Translational Research in Public Health, Newcastle University, Newcastle upon Tyne, UK.
Martin WhiteInstitute of Health & Society, Newcastle University, Newcastle upon Tyne, UK.
Jean AdamsMRC Epidemiology Unit, University of Cambridge, School of Clinical Medicine, Cambridge Biomedicine Campus, Cambridge, UK.

Funding

British Heart FoundationCancer Research UKMedical Research Council MR/K023187/1Wellcome Trust
6 · The paper itself

Abstract

Cancer diagnosis at an early stage increases the chance of curative treatment and of survival. It has been suggested that delays on the pathway from first symptom to diagnosis and treatment may be socio-economically patterned, and contribute to socio-economic differences in receipt of treatment and in cancer survival. This review aimed to assess the published evidence for socio-economic inequalities in stage at diagnosis of lung cancer, and in the length of time spent on the lung cancer pathway. MEDLINE, EMBASE and CINAHL databases were searched to locate cohort studies of adults with a primary diagnosis of lung cancer, where the outcome was stage at diagnosis or the length of time spent within an interval on the care pathway, or a suitable proxy measure, analysed according to a measure of socio-economic position. Meta-analysis was undertaken when there were studies available with suitable data. Of the 461 records screened, 39 papers were included in the review (20 from the UK) and seven in a final meta-analysis for stage at diagnosis. There was no evidence of socio-economic inequalities in late stage at diagnosis in the most, compared with the least, deprived group (OR=1.04, 95% CI=0.92 to 1.19). No socio-economic inequalities in the patient interval or in time from diagnosis to treatment were found. Socio-economic inequalities in stage at diagnosis are thought to be an important explanatory factor for survival inequalities in cancer. However, socio-economic inequalities in stage at diagnosis were not found in a meta-analysis for lung cancer. PROSPERO PROTOCOL REGISTRATION NUMBER: CRD42014007145.

Indexed as

Healthcare DisparitiesHealth Status DisparitiesEarly Detection of CancerHumansLung NeoplasmsNeoplasm StagingSocioeconomic FactorsLung Cancer

Identifiers

PMID27682330
PMCPMC5390856

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.