Evidence map›Paper›PMID 27682081›Full record

ArticleMicroorganisms2015

Genomics of Methylotrophy in Gram-Positive Methylamine-Utilizing Bacteria.

Tami L McTaggart, David A C Beck, Usanisa Setboonsarng, Nicole Shapiro, Tanja Woyke, Mary E Lidstrom, Marina G Kalyuzhnaya, Ludmila Chistoserdova

Open access · goldAbstract read
In one paragraph

Article in Microorganisms, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Tami L McTaggartDepartment of Chemical Engineering, University of Washington, Seattle, WA 98195, USA. tmctagga@uci.edu.
David A C BeckDepartment of Chemical Engineering, University of Washington, Seattle, WA 98195, USA. dacb@uw.edu.
Usanisa SetboonsarngDepartment of Chemical Engineering, University of Washington, Seattle, WA 98195, USA. lisa.setboonsarng@gmail.com.
Nicole ShapiroDOE Joint Genome Institute, Walnut Creek, CA 94598, USA. nrshapiro@lbl.gov.
Tanja WoykeDOE Joint Genome Institute, Walnut Creek, CA 94598, USA. TWoyke@lbl.gov.
Mary E LidstromDepartment of Chemical Engineering, University of Washington, Seattle, WA 98195, USA. lidstrom@uw.edu.
Marina G KalyuzhnayaDepartment of Microbiology, University of Washington, Seattle, WA 98195, USA. mkalyuzhnaya@mail.sdsu.edu.
Ludmila ChistoserdovaDepartment of Chemical Engineering, University of Washington, Seattle, WA 98195, USA. milachis@u.washington.edu.
University of Washington · USJoint Genome Institute · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gram-positive methylotrophic bacteria have been known for a long period of time, some serving as model organisms for characterizing the specific details of methylotrophy pathways/enzymes within this group. However, genome-based knowledge of methylotrophy within this group has been so far limited to a single species, Bacillus methanolicus (Firmicutes). The paucity of whole-genome data for Gram-positive methylotrophs limits our global understanding of methylotrophy within this group, including their roles in specific biogeochemical cycles, as well as their biotechnological potential. Here, we describe the isolation of seven novel strains of Gram-positive methylotrophs that include two strains of Bacillus and five representatives of Actinobacteria classified within two genera, Arthrobacter and Mycobacterium. We report whole-genome sequences for these isolates and present comparative analysis of the methylotrophy functional modules within these genomes. The genomic sequences of these seven novel organisms, all capable of growth on methylated amines, present an important reference dataset for understanding the genomic basis of methylotrophy in Gram-positive methylotrophic bacteria. This study is a major contribution to the field of methylotrophy, aimed at closing the gap in the genomic knowledge of methylotrophy within this diverse group of bacteria.

Indexed as

ArthrobacterBacillusgenomicsLake WashingtonmethylotrophyMycobacterium

Identifiers

PMID27682081
PMCPMC5023230
OpenAlexW1995675142

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.