Evidence map›Paper›PMID 27681840›Full record

ArticleThe Biochemical journal2016

Regulation of divalent metal transporter-1 by serine phosphorylation.

Young Ah Seo, Ruvin Kumara, Herbert Wetli, Marianne Wessling-Resnick

Open access · bronzeAbstract read
In one paragraph

Article in The Biochemical journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. A holistic view of mammalian (vertebrate) cellular iron uptake.Metallomics : integrated biometal science · 2020
    Review
  9. Hyperglycemia promotes microvillus membrane expression of DMT1 in intestinal epithelial cells in a PKCα-dependent manner.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2019
    Article
  10. Ferroportin disease mutations influence manganese accumulation and cytotoxicity.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2019
    Article
  11. Post-translational modifications of transporters.Pharmacology & therapeutics · 2018
    Review
  12. The Divalent Metal Transporter 1 (DMT1) Is Required for Iron Uptake and Normal Development of Oligodendrocyte Progenitor Cells.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2018
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Young Ah SeoDepartment of Genetics and Complex Diseases, Harvard School of Public Health, Boston, MA, USA.
Ruvin KumaraDepartment of Genetics and Complex Diseases, Harvard School of Public Health, Boston, MA, USA.
Herbert WetliDepartment of Genetics and Complex Diseases, Harvard School of Public Health, Boston, MA, USA.
Marianne Wessling-ResnickDepartment of Genetics and Complex Diseases, Harvard School of Public Health, Boston, MA, USA.
Harvard University · US

Funding

Microgial Iron Metabolism and Its Regulation by CannabinoidsR01DK064750 · NIDDK · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI LEE, CHIH-HAO · 2004 to 2021
$4.2M
Influence of Genetic Variation on Manganese Neurotoxicity and Parkinson's diseaseR00ES024340 · NIEHS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SEO, YOUNG AH · 2016 to 2018
$747k
Pathogenesis and Therapy of HIV-Related Neuropathic PainR21DA025527 · NIDA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HAO, SHUANGLIN · 2009 to 2010
$423k
NIDA NIH HHS R21 DA025527NIDDK NIH HHS R01 DK064750NIEHS NIH HHS R00 ES024340
6 · The paper itself

Abstract

Divalent metal transporter-1 (DMT1) mediates dietary iron uptake across the intestinal mucosa and facilitates peripheral delivery of iron released by transferrin in the endosome. Here, we report that classical cannabinoids (Δ

Indexed as

Cation Transport ProteinsHEK293 CellsHumansImmunoprecipitationIon TransportIronMutagenesis, Site-DirectedMutationOxidative StressPhosphorylationReceptor, Cannabinoid, CB2RNA, Small InterferingSerineSolute Carrier Family 11, Member 2StaurosporineCation Transport ProteinsIronReceptor, Cannabinoid, CB2RNA, Small InterferingSerineSolute Carrier Family 11, Member 2Staurosporinecannabinoid receptorDMT1iron transportSlc11a2Δ9-tetrahydrocannabinol

Identifiers

PMID27681840
PMCPMC5103878
OpenAlexW2526653747

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.