Evidence map›Paper›PMID 27681573›Full record

ArticleMycopathologia2016

Candida glabrata species complex prevalence and antifungal susceptibility testing in a culture collection: First description of Candida nivariensis in Argentina.

Soraya Eugenia Morales-López, Constanza G Taverna, María Eugenia Bosco-Borgeat, Ivana Maldonado, Walter Vivot, Wanda Szusz, Guillermo Garcia-Effron, Susana B Córdoba

Abstract read
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In one paragraph

Article in Mycopathologia, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Microorganisms · 2025
    Article
  2. Article
  3. Article
  4. Overview on the Infections Related to RarePathogens (Basel, Switzerland) · 2022
    Review
  5. Review
  6. Article
  7. Article
  8. Identification of Cryptic Species of FourJournal of fungi (Basel, Switzerland) · 2019
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Soraya Eugenia Morales-LópezDepartamento de Micología, Instituto Nacional de Enfermedades Infecciosas "Dr. Carlos G. Malbrán", Avenida Vélez Sarsfield 563, Ciudad Autónoma de Buenos Aires, Argentina.
Constanza G TavernaDepartamento de Micología, Instituto Nacional de Enfermedades Infecciosas "Dr. Carlos G. Malbrán", Avenida Vélez Sarsfield 563, Ciudad Autónoma de Buenos Aires, Argentina.
María Eugenia Bosco-BorgeatDepartamento de Micología, Instituto Nacional de Enfermedades Infecciosas "Dr. Carlos G. Malbrán", Avenida Vélez Sarsfield 563, Ciudad Autónoma de Buenos Aires, Argentina.
Ivana MaldonadoLaboratorios Domeq y Lafage, Ciudad Autónoma de Buenos Aires, Argentina.
Walter VivotDepartamento de Micología, Instituto Nacional de Enfermedades Infecciosas "Dr. Carlos G. Malbrán", Avenida Vélez Sarsfield 563, Ciudad Autónoma de Buenos Aires, Argentina.
Wanda SzuszDepartamento de Micología, Instituto Nacional de Enfermedades Infecciosas "Dr. Carlos G. Malbrán", Avenida Vélez Sarsfield 563, Ciudad Autónoma de Buenos Aires, Argentina.
Guillermo Garcia-EffronLaboratorio de Micología y Diagnóstico Molecular, Cátedra de Parasitología y Micología, Facultad de Bioquímica y Ciencias Biológicas, Universidad Nacional del Litoral, Santa Fe, Argentina.
Susana B CórdobaDepartamento de Micología, Instituto Nacional de Enfermedades Infecciosas "Dr. Carlos G. Malbrán", Avenida Vélez Sarsfield 563, Ciudad Autónoma de Buenos Aires, Argentina. sorayaeugeniam@hotmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The presence of the cryptic species belonging to the Candida glabrata complex has not been studied in Argentina. We analyzed a collection of 117 clinical isolates of C. glabrata complex belonging to a National Culture Collection of Instituto Nacional de Microbiología "Dr. Carlos G. Malbrán" from Argentina (40 isolates from blood samples, 18 from other normally sterile sites, 20 from vagina, 14 from urine, 7 from oral cavity, 3 from catheter, 1 from a stool sample and 14 isolates whose clinical origin was not recorded). The aims of this work were to determine the prevalence of the cryptic species Candida nivariensis and Candida bracarensis and to evaluate the susceptibility profile of isolates against nine antifungal drugs. Identification was carried out by using classical phenotypic tests, CHROMagar™ Candida, PCR and MALDI-TOF. The minimal inhibitory concentrations of amphotericin B, 5-fluorocytosine, fluconazole, itraconazole, voriconazole, ketoconazole, posaconazole, caspofungin and anidulafungin were determined according to the EDef 7.3 (EUCAST) reference document. Of the 117 isolates, 114 were identified as C. glabrata and three as C. nivariensis by using PCR and MALDI-TOF. There were no major differences between C. nivariensis and C. glabrata susceptibility profiles. No resistant strains were found to echinocandins. We have found that the percentage of C. nivariensis in our culture collection was 2.56. This is the first description of C. nivariensis in Argentina, and data obtained could contribute to the knowledge of the epidemiology of this cryptic species.

Indexed as

Antifungal AgentsArgentinaCandida glabrataCandidiasisCulture MediaHumansMicrobiological TechniquesMolecular Diagnostic TechniquesPolymerase Chain ReactionPrevalenceSpectrometry, Mass, Matrix-Assisted Laser Desorption-IonizationAntifungal AgentsCulture MediaAntifungal susceptibility testingCandida bracarensisCandida glabrata complexCandida nivariensisMALDI-TOFYeast identification

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.