Evidence map›Paper›PMID 27680694›Full record

SynthesisNature2016

Genome-wide associations for birth weight and correlations with adult disease.

Momoko Horikoshi, Robin N Beaumont, Felix R Day, Nicole M Warrington, Marjolein N Kooijman, Juan Fernandez-Tajes, Bjarke Feenstra, Natalie R van Zuydam, Kyle J Gaulton, Niels Grarup and 155 more

Registry-linked trialOpen access · bronzeAbstract readMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Nature, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05166447 (Twenty-year Follow-up of the Inter99 Cohort), which is not on this map. Cited by 284 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
284citing papers in PubMed, 8 pooled it
121.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05166447 enrolling by invitationnot on this mapstarted 2021, after this paper: background citation

Twenty-year Follow-up of the Inter99 Cohort

TypeobservationalSponsorBispebjerg HospitalRan2021 to 2028Enrolled4,000ConditionsCoronary Heart Disease, Acute Myocardial Infarction, Cardiovascular Diseases, Type 2 Diabetes
3 · Its place in the literature

Who cites it

284 citing papers in PubMed, 8 syntheses or guidelines pooled it, 536 citations in OpenAlex.

  1. NewbornGenes · 2025
    Pooled it
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  11. Article
  12. Article
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  14. Review
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  19. Quantifying direct genetic signal captured by principal component adjustment.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  20. Review

224 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

165 authors at 20 institutions in 16 countries.

Momoko Horikoshi *Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.
Robin N Beaumont *Institute of Biomedical and Clinical Science, University of Exeter Medical School, Royal Devon and Exeter Hospital, Exeter, UK.
Felix R Day *MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK.
Nicole M Warrington *The University of Queensland Diamantina Institute, Translational Research Institute, Brisbane, Australia.
Marjolein N Kooijman *The Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, the Netherlands.
Juan Fernandez-Tajes *Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.
Bjarke FeenstraDepartment of Epidemiology Research, Statens Serum Institute, Copenhagen, Denmark.
Natalie R van ZuydamWellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.
Kyle J GaultonWellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.
Niels GrarupThe Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Jonathan P BradfieldCenter for Applied Genomics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
David P StrachanPopulation Health Research Institute, St George's University of London, London, Cranmer Terrace, UK.
Ruifang Li-GaoDepartment of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands.
Tarunveer S AhluwaliaThe Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Eskil KreinerCOPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.
Rico RueediDepartment of Medical Genetics, University of Lausanne, Lausanne, Switzerland.
Leo-Pekka LyytikäinenDepartment of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.
Diana L CousminerInstitute for Molecular Medicine, Finland (FIMM), University of Helsinki, Helsinki, Finland.
Ying WuDepartment of Genetics, University of North Carolina, Chapel Hill, NC, USA.
Elisabeth ThieringInstitute of Epidemiology I, Helmholtz Zentrum München- German Research Center for Environmental Health, Neuherberg, Germany.
Carol A WangSchool of Women's and Infants' Health, The University of Western Australia, Perth, Australia.
Christian T HaveThe Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Jouke-Jan HottengaNetherlands Twin Register, Department of Biological Psychology, VU University, Amsterdam, the Netherlands.
Natalia Vilor-TejedorISGlobal, Centre for Research in Environmental Epidemiology (CREAL), Barcelona, Spain.
Peter K JoshiUsher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, Scotland, UK.
Eileen Tai Hui BohSaw Swee Hock School of Public Health, National University of Singapore, National University Health System, Singapore, Singapore.
Ioanna NtallaWilliam Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
Niina PitkänenResearch Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland.
Anubha MahajanWellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.
Elisabeth M van LeeuwenDepartment of Epidemiology, Erasmus MC, University Medical Center Rotterdam, the Netherlands.
Raimo JoroInstitute of Biomedicine, Physiology, University of Eastern Finland, Kuopio, Finland.
Vasiliki LagouWellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.
Michael NodzenskiDepartment of Preventive Medicine, Division of Biostatistics, Feinberg School of Medicine, Northwestern University, Chicago, USA.
Louise A DiverInstitute of Cardiovascular & Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.
Krina T ZondervanWellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.
Mariona BustamanteISGlobal, Centre for Research in Environmental Epidemiology (CREAL), Barcelona, Spain.
Pedro Marques-VidalDepartment of Internal Medicine, Internal Medicine, Lausanne University Hospital (CHUV), Lausanne, Switzerland.
Josep M MercaderJoint BSC-CRG-IRB Research Program in Computational Biology, Barcelona Supercomputing Center, Barcelona, Spain.
Amanda J BennettOxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK.
Nilufer RahmiogluWellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.
Dale R NyholtInstitute of Health and Biomedical Innovation, Queensland University of Technology, Queensland, Australia.
Ronald Ching Wan MaDepartment of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, Hong Kong, China.
Claudia Ha Ting TamDepartment of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, Hong Kong, China.
Wing Hung TamDepartment of Obstetrics and Gynaecology, The Chinese University of Hong Kong, Hong Kong, Hong Kong, China.
CHARGE Consortium Hematology Working Group
Santhi K GaneshCardiovascular Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
Frank Ja van RooijDepartment of Epidemiology, Erasmus MC, University Medical Center Rotterdam, the Netherlands.
Samuel E JonesInstitute of Biomedical and Clinical Science, University of Exeter Medical School, Royal Devon and Exeter Hospital, Exeter, UK.
Po-Ru LohDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Katherine S RuthInstitute of Biomedical and Clinical Science, University of Exeter Medical School, Royal Devon and Exeter Hospital, Exeter, UK.
Marcus A TukeInstitute of Biomedical and Clinical Science, University of Exeter Medical School, Royal Devon and Exeter Hospital, Exeter, UK.
Jessica TyrrellInstitute of Biomedical and Clinical Science, University of Exeter Medical School, Royal Devon and Exeter Hospital, Exeter, UK.
Andrew R WoodInstitute of Biomedical and Clinical Science, University of Exeter Medical School, Royal Devon and Exeter Hospital, Exeter, UK.
Hanieh YaghootkarInstitute of Biomedical and Clinical Science, University of Exeter Medical School, Royal Devon and Exeter Hospital, Exeter, UK.
Denise M ScholtensDepartment of Preventive Medicine, Division of Biostatistics, Feinberg School of Medicine, Northwestern University, Chicago, USA.
Lavinia PaternosterMedical Research Council Integrative Epidemiology Unit at the University of Bristol, Bristol, UK.
Inga ProkopenkoWellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.
Peter KovacsIFB Adiposity Diseases, University of Leipzig, Leipzig, Germany.
Mustafa AtalayInstitute of Biomedicine, Physiology, University of Eastern Finland, Kuopio, Finland.
Sara M WillemsDepartment of Epidemiology, Erasmus MC, University Medical Center Rotterdam, the Netherlands.
Kalliope PanoutsopoulouWellcome Trust Sanger Institute, Hinxton, Cambridgeshire, UK.
Xu WangSaw Swee Hock School of Public Health, National University of Singapore, National University Health System, Singapore, Singapore.
Lisbeth CarstensenDepartment of Epidemiology Research, Statens Serum Institute, Copenhagen, Denmark.
Frank GellerDepartment of Epidemiology Research, Statens Serum Institute, Copenhagen, Denmark.
Katharina E SchrautUsher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, Scotland, UK.
Mario MurciaCIBER de Epidemiología y Salud Pública (CIBERESP), Spain.
Catharina Em van BeijsterveldtNetherlands Twin Register, Department of Biological Psychology, VU University, Amsterdam, the Netherlands.
Gonneke WillemsenNetherlands Twin Register, Department of Biological Psychology, VU University, Amsterdam, the Netherlands.
Emil V R AppelThe Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Cilius E FonvigThe Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Caecilie TrierThe Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Carla Mt TieslerInstitute of Epidemiology I, Helmholtz Zentrum München- German Research Center for Environmental Health, Neuherberg, Germany.
Marie StandlInstitute of Epidemiology I, Helmholtz Zentrum München- German Research Center for Environmental Health, Neuherberg, Germany.
Zoltán KutalikSwiss Institute of Bioinformatics, Lausanne, Switzerland.
Sílvia Bonas-GuarchJoint BSC-CRG-IRB Research Program in Computational Biology, Barcelona Supercomputing Center, Barcelona, Spain.
David M HougaardDanish Center for Neonatal Screening, Statens Serum Institute, Copenhagen, Denmark.
Friman SánchezJoint BSC-CRG-IRB Research Program in Computational Biology, Barcelona Supercomputing Center, Barcelona, Spain.
David TorrentsJoint BSC-CRG-IRB Research Program in Computational Biology, Barcelona Supercomputing Center, Barcelona, Spain.
Johannes WaageCOPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.
Mads V HollegaardDanish Center for Neonatal Screening, Statens Serum Institute, Copenhagen, Denmark.
Hugoline G de HaanDepartment of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands.
Frits R RosendaalDepartment of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands.
Carolina Medina-GomezThe Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, the Netherlands.
Susan M RingMedical Research Council Integrative Epidemiology Unit at the University of Bristol, Bristol, UK.
Gibran HemaniMedical Research Council Integrative Epidemiology Unit at the University of Bristol, Bristol, UK.
George McMahonSchool of Social and Community Medicine, University of Bristol, Bristol, UK.
Neil R RobertsonWellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.
Christopher J GrovesOxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK.
Claudia LangenbergMRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK.
Jian'an LuanMRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK.
Robert A ScottMRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK.
Jing Hua ZhaoMRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK.
Frank D MentchCenter for Applied Genomics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Scott M MacKenzieInstitute of Cardiovascular & Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.
Rebecca M ReynoldsBHF Centre for Cardiovascular Science, University of Edinburgh, Queen's Medical Research Institute, Edinburgh, Scotland, UK.
Early Growth Genetics (EGG) Consortium
William L LoweDepartment of Medicine, Division of Endocrinology, Metabolism, and Molecular Medicine, Feinberg School of Medicine, Northwestern University, Chicago, USA.
Anke TönjesMedical Department, University of Leipzig, Leipzig, Germany.
Michael StumvollIFB Adiposity Diseases, University of Leipzig, Leipzig, Germany.
Virpi LindiInstitute of Biomedicine, Physiology, University of Eastern Finland, Kuopio, Finland.
Timo A LakkaInstitute of Biomedicine, Physiology, University of Eastern Finland, Kuopio, Finland.
Cornelia M van DuijnDepartment of Epidemiology, Erasmus MC, University Medical Center Rotterdam, the Netherlands.
Wieland KiessPediatric Research Center, Department of Women´s & Child Health, University of Leipzig, Leipzig, Germany.
Antje KörnerIFB Adiposity Diseases, University of Leipzig, Leipzig, Germany.
Thorkild Ia SørensenMedical Research Council Integrative Epidemiology Unit at the University of Bristol, Bristol, UK.
Harri NiinikoskiDepartment of Pediatrics, Turku University Hospital, Turku, Finland.
Katja PahkalaResearch Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland.
Olli T RaitakariResearch Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland.
Eleftheria ZegginiWellcome Trust Sanger Institute, Hinxton, Cambridgeshire, UK.
George V DedoussisDepartment of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens, Greece.
Yik-Ying TeoSaw Swee Hock School of Public Health, National University of Singapore, National University Health System, Singapore, Singapore.
Seang-Mei SawSaw Swee Hock School of Public Health, National University of Singapore, National University Health System, Singapore, Singapore.
Mads MelbyeDepartment of Epidemiology Research, Statens Serum Institute, Copenhagen, Denmark.
Harry CampbellUsher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, Scotland, UK.
James F WilsonUsher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, Scotland, UK.
Martine VrijheidISGlobal, Centre for Research in Environmental Epidemiology (CREAL), Barcelona, Spain.
Eco Jcn de GeusNetherlands Twin Register, Department of Biological Psychology, VU University, Amsterdam, the Netherlands.
Dorret I BoomsmaNetherlands Twin Register, Department of Biological Psychology, VU University, Amsterdam, the Netherlands.
Haja N KadarmideenDepartment of Large Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Jens-Christian HolmThe Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Torben HansenThe Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Sylvain SebertCenter for Life Course Health Research, Faculty of Medicine, University of Oulu, Oulu, Finland.
Andrew T HattersleyInstitute of Biomedical and Clinical Science, University of Exeter Medical School, Royal Devon and Exeter Hospital, Exeter, UK.
Lawrence J BeilinSchool of Medicine and Pharmacology, Royal Perth Hospital Unit, The University of Western Australia, Perth, Australia.
John P NewnhamSchool of Women's and Infants' Health, The University of Western Australia, Perth, Australia.
Craig E PennellSchool of Women's and Infants' Health, The University of Western Australia, Perth, Australia.
Joachim HeinrichInstitute of Epidemiology I, Helmholtz Zentrum München- German Research Center for Environmental Health, Neuherberg, Germany.
Linda S AdairDepartment of Nutrition, University of North Carolina, Chapel Hill, NC, USA.
Judith B BorjaUSC-Office of Population Studies Foundation, Inc., University of San Carlos, Cebu City, Philippines.
Karen L MohlkeDepartment of Genetics, University of North Carolina, Chapel Hill, NC, USA.
Johan G ErikssonNational Institute for Health and Welfare, Helsinki, Finland.
Elisabeth E WidénInstitute for Molecular Medicine, Finland (FIMM), University of Helsinki, Helsinki, Finland.
Mika KähönenDepartment of Clinical Physiology, Tampere University Hopital, Tampere, Finland.
Jorma S ViikariDivision of Medicine, Turku University Hospital, Turku, Finland.
Terho LehtimäkiDepartment of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.
Peter VollenweiderDepartment of Internal Medicine, Internal Medicine, Lausanne University Hospital (CHUV), Lausanne, Switzerland.
Klaus BønnelykkeCOPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.
Hans BisgaardCOPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.
Dennis O Mook-KanamoriDepartment of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands.
Albert HofmanThe Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, the Netherlands.
Fernando RivadeneiraThe Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, the Netherlands.
André G UitterlindenThe Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, the Netherlands.
Charlotta PisingerResearch Center for Prevention and Health Capital Region, Center for Sundhed, Rigshospitalet - Glostrup, Copenhagen University, Glostrup, Denmark.
Oluf PedersenThe Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Christine PowerPopulation, Policy and Practice, UCL Institute of Child Health, University College London, London, UK.
Elina HyppönenPopulation, Policy and Practice, UCL Institute of Child Health, University College London, London, UK.
Nicholas J WarehamMRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK.
Hakon HakonarsonCenter for Applied Genomics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Eleanor DaviesInstitute of Cardiovascular & Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.
Brian R WalkerBHF Centre for Cardiovascular Science, University of Edinburgh, Queen's Medical Research Institute, Edinburgh, Scotland, UK.
Vincent Wv JaddoeThe Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, the Netherlands.
Marjo-Riitta JarvelinCenter for Life Course Health Research, Faculty of Medicine, University of Oulu, Oulu, Finland.
Struan Fa GrantCenter for Applied Genomics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Allan A VaagDepartment of Clinical Medicine, Copenhagen University, Copenhagen, Denmark.
Debbie A LawlorMedical Research Council Integrative Epidemiology Unit at the University of Bristol, Bristol, UK.
Timothy M FraylingInstitute of Biomedical and Clinical Science, University of Exeter Medical School, Royal Devon and Exeter Hospital, Exeter, UK.
George Davey SmithMedical Research Council Integrative Epidemiology Unit at the University of Bristol, Bristol, UK.
Andrew P MorrisWellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.
Ken K OngMRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK.
Janine F FelixThe Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, the Netherlands.
Nicholas J TimpsonMedical Research Council Integrative Epidemiology Unit at the University of Bristol, Bristol, UK.
John Rb PerryMRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK.
David M EvansThe University of Queensland Diamantina Institute, Translational Research Institute, Brisbane, Australia.
Mark I McCarthyWellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.
Rachel M FreathyInstitute of Biomedical and Clinical Science, University of Exeter Medical School, Royal Devon and Exeter Hospital, Exeter, UK.
University of Copenhagen · DKCentre for Human Genetics · GBErasmus MC · NLUniversity of Exeter · GBUniversity of Cambridge · GBUniversity of Bristol · GBStatens Serum Institut · DKChildren's Hospital of Philadelphia · USUniversity of Turku · FIHelmholtz Zentrum München · DELeiden University Medical Center · NLNational University of Singapore · SGThe University of Western Australia · AUUniversity of Eastern Finland · FIBarcelona Supercomputing Center · ESChinese University of Hong Kong · HKNorthwestern University · USTampere University · FIUniversitat Pompeu Fabra · ESUniversity of Edinburgh · GB

Funding

Research Services CoreP2CHD050924 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI KAREN B GUZZO · 2015 to 2026
$9.6M
Genome Wide Association Study for Childhood ObesityR01HD056465 · NICHD · CHILDREN'S HOSP OF PHILADELPHIA · PI GRANT, STRUAN F A · 2008 to 2024
$9.5M
Genetic Studies of The Impact of Hematologic Traits On Cardiovascular DiseaseR01HL122684 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI GANESH, SANTHI K · 2015 to 2019
$3.4M
British Heart Foundation RG/11/4/28734Chief Scientist Office CZB/4/733Medical Research Council G0500070Medical Research Council G0600705Medical Research Council G0601261Medical Research Council G1001799Medical Research Council G9815508Medical Research Council MC_PC_15018Medical Research Council MC_PC_U127561128Medical Research Council MC_QA137853Medical Research Council MC_U106179471Medical Research Council MC_U106179472Medical Research Council MC_UU_12013/1Medical Research Council MC_UU_12013/3Medical Research Council MC_UU_12013/4Medical Research Council MC_UU_12013/5Medical Research Council MC_UU_12015/1Medical Research Council MC_UU_12015/2Medical Research Council MR/J012165/1Medical Research Council MR/K011480/1Medical Research Council MR/M005070/1Wellcome Trust 104150Wellcome Trust 202802/Z/16/Z
6 · The paper itself

Abstract

Birth weight (BW) has been shown to be influenced by both fetal and maternal factors and in observational studies is reproducibly associated with future risk of adult metabolic diseases including type 2 diabetes (T2D) and cardiovascular disease. These life-course associations have often been attributed to the impact of an adverse early life environment. Here, we performed a multi-ancestry genome-wide association study (GWAS) meta-analysis of BW in 153,781 individuals, identifying 60 loci where fetal genotype was associated with BW (P < 5 × 10

Indexed as

Genetic Predisposition to DiseaseGenome-Wide Association StudyAdultAgingAnthropometryBirth WeightBlood PressureChromatin Assembly and DisassemblyCohort StudiesCoronary Artery DiseaseDatasets as TopicDiabetes Mellitus, Type 2FemaleFetusGenetic LociGenetic VariationGlucoseGlycogenInsulin

Identifiers

PMID27680694
PMCPMC5164934
OpenAlexW2510387549

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.