ArticlePloS one
Hedgehogs and Mustelid Species: Major Carriers of Pathogenic Leptospira, a Survey in 28 Animal Species in France (20122015).
Article in PloS one. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
37 citing papers in PubMed, 1 synthesis or guideline pooled it, 64 citations in OpenAlex.
- A systematic review of leptospirosis on wild animals in Latin America.Tropical animal health and production · 2018Pooled it
- A systematic review ofOne health (Amsterdam, Netherlands) · 2026Article
- A systematic review and meta-analysis ofOne health (Amsterdam, Netherlands) · 2026Review
- Serological and molecular evidence of Leptospira spp. in martens from Poland.BMC veterinary research · 2026Article
- Molecular survey and risk factors ofParasitology · 2026Article
- Molecular study of Francisella spp. from ticks in hedgehogs (Erinaceus europaeus) in urban-suburban areas of West Azerbaijan Province.BMC veterinary research · 2025Article
- Chronic Carriage of Leptospira interrogans Genotype Associated With the Australis Serogroup by Naturally-Infected Hedgehogs ( Erinaceus europaeus ) at a Wildlife Health Centre in Northwestern France.Zoonoses and public health · 2025Article
- Leptospirosis in Unconventional Mammal Pets.Veterinary sciences · 2025Review
- Look and you will find-a literature review of new strains of Leptospira spp., 2000-2025.FEMS microbiology reviews · 2025Review
- Characterisation of pathogenicEpidemiology and infection · 2024Article
- Isolation of VirulentMicroorganisms · 2024Article
- Tracking potentialOne health (Amsterdam, Netherlands) · 2024Article
- Article
- Detection and Identification of PathogenicTransboundary and emerging diseases · 2024Article
- Spatiotemporal Distribution ofPathogens (Basel, Switzerland) · 2023Article
- White-Toothed Shrews (GenusPathogens (Basel, Switzerland) · 2023Article
- Synanthropic and Wild Animals as Sentinels of Zoonotic Agents: A Study ofInternational journal of environmental research and public health · 2023Article
- Identification of PathogenicPathogens (Basel, Switzerland) · 2023Article
- Genetic diversity ofFrontiers in cellular and infection microbiology · 2023Article
- Molecular and Serological Identification of PathogenicTransboundary and emerging diseases · 2023Article
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Human leptospirosis is a zoonotic and potentially fatal disease that has increasingly been reported in both developing and developed countries, including France. However, our understanding of the basic aspects of the epidemiology of this disease, including the source of Leptospira serogroup Australis infections in humans and domestic animals, remains incomplete. We investigated the genetic diversity of Leptospira in 28 species of wildlife other than rats using variable number tandem repeat (VNTR) and multispacer sequence typing (MST). The DNA of pathogenic Leptospira was detected in the kidney tissues of 201 individuals out of 3,738 tested individuals. A wide diversity, including 50 VNTR profiles and 8 MST profiles, was observed. Hedgehogs and mustelid species had the highest risk of being infected (logistic regression, OR = 66.8, CI95% = 30.9-144 and OR = 16.7, CI95% = 8.7-31.8, respectively). Almost all genetic profiles obtained from the hedgehogs were related to Leptospira interrogans Australis, suggesting the latter as a host-adapted bacterium, whereas mustelid species were infected by various genotypes, suggesting their interaction with Leptospira was different. By providing an inventory of the circulating strains of Leptospira and by pointing to hedgehogs as a potential reservoir of L. interrogans Australis, our study advances current knowledge on Leptospira animal carriers, and this information could serve to enhance epidemiological investigations in the future.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.