Evidence map›Paper›PMID 27680390›Full record

Trial reportJournal of human hypertension2017

A randomized controlled trial to assess the central hemodynamic response to exercise in patients with transient ischaemic attack and minor stroke.

J Faulkner, Y-C Tzeng, D Lambrick, B Woolley, P D Allan, T O'Donnell, J Lanford, L Wong, L Stoner

Open access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of human hypertension, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 4 pooled it
0.7field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 syntheses or guidelines pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Physical fitness training for stroke patients.The Cochrane database of systematic reviews · 2020
    Pooled it
  3. Pooled it
  4. Pooled it
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 3 countries.

J FaulknerDepartment of Sport and Exercise, University of Winchester, Winchester, UK.
Y-C TzengCentre for Translational Physiology, University of Otago, Wellington, New Zealand.
D LambrickFaculty of Health Sciences, University of Southampton, Southampton, UK.
B WoolleySchool of Sport and Exercise, Massey University, Massey, New Zealand.
P D AllanCentre for Translational Physiology, University of Otago, Wellington, New Zealand.
T O'DonnellCentre for Translational Physiology, University of Otago, Wellington, New Zealand.
J LanfordNeurology, Wellington Hospital, Wellington, New Zealand.
L WongNeurology, Wellington Hospital, Wellington, New Zealand.
L StonerDepartment of Exercise and Sport Science, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
University of Otago · NZWellington Hospital · NZMassey University · NZUniversity of North Carolina at Chapel Hill · USUniversity of Southampton · GBUniversity of Winchester · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Early exercise engagement elicits meaningful changes in peripheral blood pressure in patients diagnosed with transient ischaemic attack (TIA) or minor stroke. However, central hemodynamic markers may provide clinicians with important diagnostic and prognostic information beyond that provided by peripheral blood pressure readings. The purpose of this single-centre, randomized, parallel-group clinical trial was to determine the effect of a 12-week aerobic exercise intervention on central and peripheral hemodynamic variables in patients with TIA or minor stroke. In this study, 47 participants (66±10 years) completed a baseline assessment, which involved the measurement of central and peripheral hemodynamic parameters, undertaken in the morning, in a fasted state. Participants were randomized to either a 12-week exercise or control group on completion of the baseline assessment. An identical follow-up assessment was completed post intervention. Central hemodynamic variables were assessed using an oscillometric device at both assessments. Analysis of covariance demonstrated a significant interaction for central and peripheral blood pressure and augmentation index (all P<0.05; η

Indexed as

HemodynamicsStroke RehabilitationAgedExerciseFemaleHumansIschemic Attack, TransientMaleMiddle Aged

Identifiers

PMID27680390
PMCPMC5301081
OpenAlexW2523906211

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.