Trial reportPediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies2016
Pediatric Out-of-Hospital Cardiac Arrest Characteristics and Their Association With Survival and Neurobehavioral Outcome.
Trial report in Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
42 citing papers in PubMed, 1 synthesis or guideline pooled it, 98 citations in OpenAlex.
- Epinephrine in pediatric cardiorespiratory arrest: when and how much?Einstein (Sao Paulo, Brazil) · 2020Pooled it
- Impact of blended learning on manual defibrillator's use: A simulation-based randomized trial.Nursing in critical care · 2022Trial
- Cardiac Arrest Outcomes in Children With Preexisting Neurobehavioral Impairment.Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2019Trial
- Pediatric out-of-hospital cardiac arrest: Time to goal target temperature and outcomes.Resuscitation · 2019Trial
- Therapeutic hypothermia after paediatric cardiac arrest: Pooled randomized controlled trials.Resuscitation · 2018Trial
- Paediatric in-hospital cardiac arrest: Factors associated with survival and neurobehavioural outcome one year later.Resuscitation · 2018Trial
- Trial
- Pediatric cardiac arrest due to drowning and other respiratory etiologies: Neurobehavioral outcomes in initially comatose children.Resuscitation · 2017Trial
- Aetiology-dependent short- and long-term survival after paediatric out-of-hospital cardiac arrest: a multicentre, retrospective, cohort study.BMC emergency medicine · 2026Article
- Microbial characteristics and risk factors in PICU with freshwater drowning-associated pneumonia.European journal of pediatrics · 2026Article
- Outcomes of children with out-of-hospital cardiac arrest admitted to the pediatric intensive care unit after the return of spontaneous circulation: A multi-center retrospective study.European journal of pediatrics · 2025Article
- Current practice in pediatric post-cardiac arrest care: a national survey among Italian pediatric intensivists.Resuscitation plus · 2025Article
- Characteristics, Outcomes and Mortality Risk Factors of Pediatric In-Hospital Cardiac Arrest in Western China: A Retrospective Study Using Utstein Style.Children (Basel, Switzerland) · 2025Article
- COVID-19 and pediatric out-of-hospital cardiac arrest using U.S. registry database.Resuscitation plus · 2025Article
- To intubate or to resuscitate: the effect of simulation-based training on advanced airway management during simulated paediatric resuscitations.Advances in simulation (London, England) · 2025Article
- Cardiopulmonary resuscitation in obese patients: A scoping review.Resuscitation plus · 2024Article
- Cognitive outcome and its neural correlates after cardiorespiratory arrest in childhood.Developmental science · 2024Article
- Management of Paediatric Cardiac Arrest due to Shockable Rhythm-A Simulation-Based Study at Children's Hospitals in a German Federal State.Children (Basel, Switzerland) · 2024Article
- The link between initial cardiac rhythm and survival outcomes in in-hospital cardiac arrest using propensity score matching, adjustment, and weighting.Scientific reports · 2024Article
- Hospital ECMO capability is associated with survival in pediatric cardiac arrest.Resuscitation · 2023Article
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 1 country.
Funding
Abstract
objectiveTo investigate relationships between cardiac arrest characteristics and survival and neurobehavioral outcome among children recruited to the Therapeutic Hypothermia after Pediatric Cardiac Arrest Out-of-Hospital trial.
designSecondary analysis of Therapeutic Hypothermia after Pediatric Cardiac Arrest Out-of-Hospital trial data.
settingThirty-six PICUs in the United States and Canada. PATIENTS: All children (n = 295) had chest compressions for greater than or equal to 2 minutes, were comatose, and required mechanical ventilation after return of circulation.
interventionsNeurobehavioral function was assessed using the Vineland Adaptive Behavior Scales, Second Edition at baseline (reflecting prearrest status) and 12 months postarrest. U.S. norms for Vineland Adaptive Behavior Scales, Second Edition scores are 100 (mean) ± 15 (SD). Higher scores indicate better functioning. Outcomes included 12-month survival and 12-month survival with Vineland Adaptive Behavior Scales, Second Edition greater than or equal to 70. MEASUREMENT AND MAIN
resultsCardiac etiology of arrest, initial arrest rhythm of ventricular fibrillation/tachycardia, shorter duration of chest compressions, compressions not required at hospital arrival, fewer epinephrine doses, and witnessed arrest were associated with greater 12-month survival and 12-month survival with Vineland Adaptive Behavior Scales, Second Edition greater than or equal to 70. Weekend arrest was associated with lower 12-month survival. Body habitus was associated with 12-month survival with Vineland Adaptive Behavior Scales, Second Edition greater than or equal to 70; underweight children had better outcomes, and obese children had worse outcomes. On multivariate analysis, acute life threatening event/sudden unexpected infant death, chest compressions more than 30 minutes, and weekend arrest were associated with lower 12-month survival; witnessed arrest was associated with greater 12-month survival. Acute life threatening event/sudden unexpected infant death, other respiratory causes of arrest except drowning, other/unknown causes of arrest, and compressions more than 30 minutes were associated with lower 12-month survival with Vineland Adaptive Behavior Scales, Second Edition greater than or equal to 70.
conclusionsMany factors are associated with survival and neurobehavioral outcome among children who are comatose and require mechanical ventilation after out-of-hospital cardiac arrest. These factors may be useful for identifying children at risk for poor outcomes, and for improving prevention and resuscitation strategies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.