ArticleIranian journal of radiology : a quarterly journal published by the Iranian Radiological Society2016
Diagnostic Accuracy of Coronary Calcium Score Less than 100 in Excluding Coronary Artery Disease.
Article in Iranian journal of radiology : a quarterly journal published by the Iranian Radiological Society, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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10 citing papers in PubMed, 19 citations in OpenAlex.
- Utilizing the coronary artery calcium score to predict coronary artery disease in individuals with presumed cardiac symptoms: A diagnostic study.American heart journal plus : cardiology research and practice · 2026Article
- AI-driven tongue image analysis for diagnosing and predicting coronary artery disease.Scientific reports · 2025Article
- Coronary Calcium Scoring as Prediction of Coronary Artery Diseases with Low-Dose Dual-Source CT.Journal of cardiovascular development and disease · 2025Article
- Combining anatomical and biochemical markers in the detection and risk stratification of coronary artery disease.European heart journal. Cardiovascular Imaging · 2024Article
- Association between Brachial Flow-Mediated Dilation and Calcium Score in Patients with Symptomatic CAD.International journal of preventive medicine · 2023Article
- Coronary calcification and bone microarchitecture by high-resolution peripheral quantitative computed tomography from the São Paulo Ageing and Health (SPAH) Study.Scientific reports · 2022Article
- Article
- Protective effect of microRNA‑381 against inflammatory damage of endothelial cells during coronary heart disease by targeting CXCR4.Molecular medicine reports · 2020Article
- Sinogram-Affirmed Iterative Reconstruction Negatively Impacts the Risk Category Based on Agatston Score: A Study Combining Coronary Calcium Score Measurement and Coronary CT Angiography.BioMed research international · 2020Article
- Coronary artery CT calcium score assessed by direct calcium quantification using atomic absorption spectroscopy and compared to macroscopic and histological assessments.International journal of legal medicine · 2019Article
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5 authors at 1 institution in 1 country.
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Abstract
backgroundCoronary artery calcium score (CACS) is a quantitative assessment of calcifications and an established predictor of cardiovascular events.
objectivesIn this study, we evaluated the diagnostic accuracy, negative predictive value (NPV), positive predictive value (PPV), specificity and sensitivity of CACS less than 100 in predicting significant coronary artery stenosis in patients with risk of coronary artery disease (CAD) in a vessel-based analysis. PATIENTS AND
methodsA cross sectional study was carried out on a study population of 2527 consecutive stable patients with symptoms suggestive of CAD who were referred for coronary computed tomographic angiography (CCTA). We performed 1343 studies with 256 slice machine in Shahid Rajaee hospital and the other studies were carried out with 64 slice machine in Imam Khomeini hospital and the calcium score was quantified according to the Agatston method.
resultsAt the cutoff point of 100 for coronary calcium scoring, there was high specificity (87%), high sensitivity (79%), high efficiency (84%), high PPV (79%), and high NPV (87%) in the diagnosis of significant stenosis in the whole heart. The frequency of zero calcium scoring was 59% in normal or nonsignificant stenosis and 7.6% in significant stenosis in the whole heart. Calcium scoring increased with greater severity of the arterial stenosis (P values < 0.001).
conclusionWe conclude that coronary calcium scoring provided useful information in the management of patients. In CACS less than 100, it has a NPV of 87% in excluding significant stenosis in patients with the risk of CAD but it does not have enough diagnostic accuracy for surely excluding coronary stenosis, so we should perform a combination of CACS and coronary CT angiography for patients.
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