Evidence map›Paper›PMID 27679682›Full record

ArticleThe World Allergy Organization journal2016

International Consensus (ICON): allergic reactions to vaccines.

Stephen C Dreskin, Neal A Halsey, John M Kelso, Robert A Wood, Donna S Hummell, Kathryn M Edwards, Jean-Christoph Caubet, Renata J M Engler, Michael S Gold, Claude Ponvert and 6 more

Open access · goldAbstract read
In one paragraph

Article in The World Allergy Organization journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
75citing papers in PubMed, 1 pooled it
9.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

75 citing papers in PubMed, 1 synthesis or guideline pooled it, 194 citations in OpenAlex.

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  18. Safe administration of yellow fever vaccine in patients with suspected egg allergy.The journal of allergy and clinical immunology. Global · 2023
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  20. Observational

15 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 8 institutions in 3 countries.

Stephen C DreskinDivision of Allergy and Clinical Immunology, Department of Medicine, University of Colorado Denver School of Medicine, Aurora, CO USA.
Neal A HalseyInstitute for Vaccine Safety, Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD USA.
John M KelsoDivision of Allergy, Asthma, and Immunology, Scripps Clinic, San Diego, CA USA.
Robert A WoodThe Division of Pediatric Allergy and Immunology, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD USA.
Donna S HummellDivision of Pediatric Allergy, Immunology, and Pulmonary Medicine, Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, TN USA.
Kathryn M EdwardsDivision of Pediatric Infectious Diseases, Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, TN USA.
Jean-Christoph CaubetDepartment of Pediatrics, University Hospitals of Geneva and Medical School, University of Geneva, Geneva, Switzerland.
Renata J M EnglerDepartment of Medicine and Pediatrics, Uniformed Services University of the Health Sciences, Allergy-Immunology-Immunization, Walter Reed National Military Medical Center, Bethesda, MD USA.
Michael S GoldDisipline of Paediatrics, School of Medicine, University of Adelaide, Adelaide, South Australia Australia.
Claude PonvertDepartment Paediatrics, Pulmonology and Allergy service, Necker-Enfants Malades Hospital, 149 rue de Sèvres, 75015 Paris, France.
Pascal DemolyDépartement de Pneumologie et Addictologie, Hôpital Arnaud de Villeneuve - University Hospital of Montpellier, 34295 Montpellier cedex 05 - FRANCE and Sorbonne Universités, UPMC Paris 06, UMR-S 1136 INSERM, IPLESP, Equipe EPAR, 75013 Paris, France.
Mario Sanchez-BorgesAllergy and Clinical Immunology Department, Centro Médico Docente La Trinidad, Caracas, Venezuela.
Antonella MuraroFood Allergy Referral Centre Department of Women and Child health, University of Padua, Padua, Italy.
James T LiDivision of Allergic Diseases, Mayo Clinic, Rochester, MN USA.
Menachem RottemAllergy Asthma and Immunology, Emek Medical Center, Afula, and the Rappaport Faculty of Medicine, Technion- Israel Institute of Technology, Haifa, Israel.
Lanny J RosenwasserAllergy-Immunology Division, Children's Mercy Hospital and the University of Missouri-Kansas City School of Medicine, Kansas City, MO USA.
Centro Médico Docente La Trinidad · VEJohns Hopkins Medicine · USJohns Hopkins University · USMayo Clinic · USScripps Clinic · USUniversity Hospital of Geneva · CHUniversity of Colorado Denver · USVanderbilt University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRoutine immunization, one of the most effective public health interventions, has effectively reduced death and morbidity due to a variety of infectious diseases. However, allergic reactions to vaccines occur very rarely and can be life threatening. Given the large numbers of vaccines administered worldwide, there is a need for an international consensus regarding the evaluation and management of allergic reactions to vaccines.

methodsFollowing a review of the literature, and with the active participation of representatives from the World Allergy Organization (WAO), the European Academy of Allergy and Clinical Immunology (EAACI), the American Academy of Allergy, Asthma, and Immunology (AAAAI), and the American College of Allergy, Asthma, and Immunology (ACAAI), the final committee was formed with the purpose of having members who represented a wide-range of countries, had previously worked on vaccine safety, and included both allergist/immunologists as well as vaccinologists.

resultsConsensus was reached on a variety of topics, including: definition of immediate allergic reactions, including anaphylaxis, approaches to distinguish association from causality, approaches to patients with a history of an allergic reaction to a previous vaccine, and approaches to patients with a history of an allergic reaction to components of vaccines.

conclusionsThis document provides comprehensive and internationally accepted guidelines and access to on-line documents to help practitioners around the world identify allergic reactions following immunization. It also provides a framework for the evaluation and further management of patients who present either following an allergic reaction to a vaccine or with a history of allergy to a component of vaccines.

Indexed as

Allergic reactionsAllergyAnaphylaxisCausalityComponentsConsensusInternationalVaccine

Identifiers

PMID27679682
PMCPMC5026780
OpenAlexW2520200809

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.