Evidence map›Paper›PMID 27679612›Full record

ArticleFrontiers in microbiology2016

Evaluation of Staphylococcus aureus Lipoproteins: Role in Nutritional Acquisition and Pathogenicity.

Shideh V Shahmirzadi, Minh-Thu Nguyen, Friedrich Götz

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 63 citations in OpenAlex.

  1. Article
  2. Article
  3. Mutation of lipoprotein processing pathway geneAntimicrobial agents and chemotherapy · 2026
    Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. A Comparison of the Adaptive Response ofFrontiers in microbiology · 2022
    Article
  14. Frontiers in microbiology · 2022
    Review
  15. Article
  16. Lipoproteins Are Responsible for the Pro-Inflammatory Property ofInternational journal of molecular sciences · 2021
    Article
  17. Article
  18. Article
  19. Article
  20. LipoproteinmBio · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Shideh V ShahmirzadiMicrobial Genetics, Interfaculty Institute of Microbiology and Infection Medicine, University of Tübingen Tübingen, Germany.
Minh-Thu NguyenMicrobial Genetics, Interfaculty Institute of Microbiology and Infection Medicine, University of Tübingen Tübingen, Germany.
Friedrich GötzMicrobial Genetics, Interfaculty Institute of Microbiology and Infection Medicine, University of Tübingen Tübingen, Germany.
University of Tübingen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacterial lipoproteins (Lpp) represent a major class of membrane proteins. They are distinguished by a lipid moiety at the N-terminus by which they are anchored either in the outer leaflet of the cytoplasmic membrane or, in Gram-negative bacteria, also in the inner leaflet of the outer membrane. In Gram-positive bacteria Lpp significantly contribute to nutrient transport, Toll-like receptor 2 activation and pathogenicity. Here we examine the Lpp of Staphylococcus aureus USA300, as a prototype for a multiple antibiotic resistant and community-acquired pathogen that is rapidly spreading worldwide. The compiled Lpp were grouped according to the postulated function and dissemination of homologs in the genus Staphylococcus and beyond. Based on this evaluation we also point out Lpp as promising vaccine candidates.

Indexed as

ion transporterslipoproteinlipoprotein disseminationlipoprotein functionspathogenicityS. aureus USA300Staphylococcus

Identifiers

PMID27679612
PMCPMC5020093
OpenAlexW2519601881

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.