Evidence map›Paper›PMID 27679529›Full record

ArticleThe Journal of biological chemistry2016

A Cytosolic Amphiphilic α-Helix Controls the Activity of the Bile Acid-sensitive Ion Channel (BASIC).

Axel Schmidt, Daniel Löhrer, Richard J Alsop, Pia Lenzig, Adrienne Oslender-Bujotzek, Monika Wirtz, Maikel C Rheinstädter, Stefan Gründer, Dominik Wiemuth

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of biological chemistry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Bile acids and salt-sensitive hypertension: a role of the gut-liver axis.American journal of physiology. Heart and circulatory physiology · 2022
    Review
  4. Murine epithelial sodium (NaThe Journal of biological chemistry · 2019
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Axel SchmidtFrom the Institute of Physiology, RWTH Aachen University, D-52074 Aachen, Germany and.
Daniel LöhrerFrom the Institute of Physiology, RWTH Aachen University, D-52074 Aachen, Germany and.
Richard J Alsopthe Department of Physics and Astronomy, McMaster University, Hamilton, Ontario L8S 4M1, Canada.
Pia LenzigFrom the Institute of Physiology, RWTH Aachen University, D-52074 Aachen, Germany and.
Adrienne Oslender-BujotzekFrom the Institute of Physiology, RWTH Aachen University, D-52074 Aachen, Germany and.
Monika WirtzFrom the Institute of Physiology, RWTH Aachen University, D-52074 Aachen, Germany and.
Maikel C Rheinstädterthe Department of Physics and Astronomy, McMaster University, Hamilton, Ontario L8S 4M1, Canada.
Stefan GründerFrom the Institute of Physiology, RWTH Aachen University, D-52074 Aachen, Germany and.
Dominik WiemuthFrom the Institute of Physiology, RWTH Aachen University, D-52074 Aachen, Germany and. Electronic address: dwiemuth@ukaachen.de.
RWTH Aachen University · DEMcMaster University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The bile acid-sensitive ion channel (BASIC) is a member of the degenerin/epithelial Na

Indexed as

AnimalsCell MembraneCytosolHumansOrganic Anion Transporters, Sodium-DependentProtein DomainsProtein Structure, SecondaryRatsSymportersXenopus laevisOrganic Anion Transporters, Sodium-Dependentsodium-bile acid cotransporterSymportersamphiphilic helixBASICbile acidBLINaCcholesterolDeg/ENaCion channelpatch clampXenopusX-ray scattering

Identifiers

PMID27679529
PMCPMC5114408
OpenAlexW2525582001

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.