Evidence map›Paper›PMID 27679478›Full record

ArticleNucleic acids research2017

Influenza Research Database: An integrated bioinformatics resource for influenza virus research.

Yun Zhang, Brian D Aevermann, Tavis K Anderson, David F Burke, Gwenaelle Dauphin, Zhiping Gu, Sherry He, Sanjeev Kumar, Christopher N Larsen, Alexandra J Lee and 18 more

Abstract read
In one paragraph

Article in Nucleic acids research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 213 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
213citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

213 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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153 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors.

Yun ZhangJ. Craig Venter Institute, La Jolla, CA 92037, USA.
Brian D AevermannJ. Craig Venter Institute, La Jolla, CA 92037, USA.
Tavis K AndersonVirus and Prion Research Unit, National Animal Disease Center, USDA-ARS, Ames, IA 50010, USA.
David F BurkeDepartment of Zoology, University of Cambridge, Cambridge, CB2 3EJ, UK.
Gwenaelle DauphinAnimal Health Service, Food and Agriculture Organization of the United Nations, Rome 00153, Italy.
Zhiping GuNorthrop Grumman Health Solutions, Rockville, MD 20850, USA.
Sherry HeNorthrop Grumman Health Solutions, Rockville, MD 20850, USA.
Sanjeev KumarNorthrop Grumman Health Solutions, Rockville, MD 20850, USA.
Christopher N LarsenVecna Technologies, Greenbelt, MD 20770, USA.
Alexandra J LeeJ. Craig Venter Institute, La Jolla, CA 92037, USA.
Xiaomei LiNorthrop Grumman Health Solutions, Rockville, MD 20850, USA.
Catherine MackenBioinformatics Institute, University of Auckland, Auckland 1010, New Zealand.
Colin MahaffeyNorthrop Grumman Health Solutions, Rockville, MD 20850, USA.
Brett E PickettJ. Craig Venter Institute, La Jolla, CA 92037, USA.
Brian ReardonJ. Craig Venter Institute, La Jolla, CA 92037, USA.
Thomas SmithNorthrop Grumman Health Solutions, Rockville, MD 20850, USA.
Lucy StewartJ. Craig Venter Institute, La Jolla, CA 92037, USA.
Christian SulowayNorthrop Grumman Health Solutions, Rockville, MD 20850, USA.
Guangyu SunVecna Technologies, Greenbelt, MD 20770, USA.
Lei TongNorthrop Grumman Health Solutions, Rockville, MD 20850, USA.
Amy L VincentVirus and Prion Research Unit, National Animal Disease Center, USDA-ARS, Ames, IA 50010, USA.
Bryan WaltersNorthrop Grumman Health Solutions, Rockville, MD 20850, USA.
Sam ZarembaNorthrop Grumman Health Solutions, Rockville, MD 20850, USA.
Hongtao ZhaoNorthrop Grumman Health Solutions, Rockville, MD 20850, USA.
Liwei ZhouNorthrop Grumman Health Solutions, Rockville, MD 20850, USA.
Christian ZmasekJ. Craig Venter Institute, La Jolla, CA 92037, USA.
Edward B KlemNorthrop Grumman Health Solutions, Rockville, MD 20850, USA.
Richard H ScheuermannJ. Craig Venter Institute, La Jolla, CA 92037, USA rscheuermann@jcvi.org.

Funding

NIAID NIH HHS HHSN272201400028C
6 · The paper itself

Abstract

The Influenza Research Database (IRD) is a U.S. National Institute of Allergy and Infectious Diseases (NIAID)-sponsored Bioinformatics Resource Center dedicated to providing bioinformatics support for influenza virus research. IRD facilitates the research and development of vaccines, diagnostics and therapeutics against influenza virus by providing a comprehensive collection of influenza-related data integrated from various sources, a growing suite of analysis and visualization tools for data mining and hypothesis generation, personal workbench spaces for data storage and sharing, and active user community support. Here, we describe the recent improvements in IRD including the use of cloud and high performance computing resources, analysis and visualization of user-provided sequence data with associated metadata, predictions of novel variant proteins, annotations of phenotype-associated sequence markers and their predicted phenotypic effects, hemagglutinin (HA) clade classifications, an automated tool for HA subtype numbering conversion, linkouts to disease event data and the addition of host factor and antiviral drug components. All data and tools are freely available without restriction from the IRD website at https://www.fludb.org.

Indexed as

Databases, FactualInfluenza A virusResearchSoftwareComputational BiologyMolecular TypingPhenotypePhylogenyViral ProteinsVirulenceViral Proteins

Identifiers

PMID27679478
PMCPMC5210613

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.