Evidence map›Paper›PMID 27678503›Full record

ArticleJournal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract2017

Perioperative Hyperglycemia and Postoperative Outcomes in Patients Undergoing Resection of Colorectal Liver Metastases.

Georgios Antonios Margonis, Neda Amini, Kazunari Sasaki, Yuhree Kim, Katiuscha Merath, Stefan Buettner, Emmanouil Pikoulis, Nikolaos Andreatos, Doris Wagner, Efstathios Antoniou and 1 more

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Article in Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Association Between Intraoperative Blood Glucose and Anastomotic Leakage in Colorectal Surgery.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2021
    Observational
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Georgios Antonios MargonisDepartment of Surgery, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Neda AminiDepartment of Surgery, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Kazunari SasakiDepartment of Surgery, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Yuhree KimDepartment of Surgery, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Katiuscha MerathDepartment of Surgery, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Stefan BuettnerDepartment of Surgery, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Emmanouil PikoulisFirst Department of Surgery, Laiko Hospital, University of Athens, Athens, Greece.
Nikolaos AndreatosDepartment of Surgery, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Doris WagnerDepartment of Surgery, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Efstathios AntoniouSecond Department of Propaedeutic Surgery, Laiko Hospital, University of Athens, Athens, Greece.
Timothy M PawlikDepartment of Surgery, The Johns Hopkins University School of Medicine, Baltimore, MD, USA. tim.pawlik@osumc.edu.
Johns Hopkins Medicine · USJohns Hopkins University · USLaiko General Hospital of Athens · GRNational and Kapodistrian University of Athens · GRThe Ohio State University Wexner Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThere is limited evidence characterizing the impact of glycemic alterations on short-term outcomes among patients undergoing resection of colorectal liver metastases (CRLM).

methodsHyperglycemia was defined as a glucose value >125 mg/dl according to WHO definition. The impact of early postoperative hyperglycemia on short-term postoperative outcomes was assessed.

resultsThe mean postoperative glucose value was 128 mg/dl; 30 (9.8 %) patients had normal fasting glucose (<100 mg/dl), 106 patients had glucose intolerance (100-125 mg/dl), and 170 (55.5 %) patients had hyperglycemia (>125 mg/dl). A postoperative complication occurred in 101 patients (morbidity, 33.1 %); among patients who experienced a complication, an infectious complication was most common (38.6 %). After controlling for clinical factors, patients with hyperglycemia had an increased risk of overall complications [odds ratio (OR) 4.11; 95 % confidence interval (CI) 1.96-8.62, P < 0.001]. This was the case for both patients with and without diabetes (P < 0.05). Patients with hyperglycemia on the day of surgery were also at an increased risk of infections [OR 9.17; 95 % CI 2.26-37.13, P = 0.002] and had a longer hospital stay (normal glucose, 4 days vs. glucose 100-125 mg/dl, 4 days vs. glucose >125 mg/dl, 5 days, P < 0.001).

conclusionsEarly postoperative hyperglycemia was associated with adverse outcomes in patients with and without diabetes who underwent resection of CRLM. Perioperative glucose evaluation may be an important quality target.

Indexed as

AgedBlood GlucoseColorectal NeoplasmsDiabetes MellitusFemaleHepatectomyHumansHyperglycemiaLiver NeoplasmsMaleMiddle AgedPerioperative PeriodPostoperative PeriodRetrospective StudiesTreatment OutcomeBlood GlucoseCRLMHyperglycemiaShort-term outcomes

Identifiers

PMID27678503
OpenAlexW2525797490

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.