Evidence map›Paper›PMID 27678363›Full record

Observational studyWorld journal of gastroenterology2016

Risk factors for postoperative pancreatic fistula: Analysis of 539 successive cases of pancreaticoduodenectomy.

Bing-Yang Hu, Tao Wan, Wen-Zhi Zhang, Jia-Hong Dong

Registry-linked trialOpen access · hybridAbstract readObservational Study
In one paragraph

Observational study in World journal of gastroenterology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06198400 (Indocyanine Green Fluorescence in Evaluation of Post-resection Pancreatic Remnant Perfusion After Pancreaticoduodenectomy), which is not on this map. Cited by 88 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
88citing papers in PubMed, 8 pooled it
6.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06198400 narecruitingnot on this mapstarted 2024, after this paper: background citation

Indocyanine Green Fluorescence in Evaluation of Post-resection Pancreatic Remnant Perfusion After Pancreaticoduodenectomy

TypeinterventionalSponsorCharles University, Czech RepublicRan2024 to 2027Enrolled60ConditionsPancreatic FistulaArmsPerioperative assessment of the perfusion of post-resection pancreatic remnant using indocyanine green-VerDye
3 · Its place in the literature

Who cites it

88 citing papers in PubMed, 8 syntheses or guidelines pooled it, 155 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Pooled it
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

28 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Bing-Yang HuBing-Yang Hu, Tao Wan, Wen-Zhi Zhang, Jia-Hong Dong, Institute and Hospital of Hepatobiliary Surgery, Chinese PLA General Hospital, Beijing 100853, China.
Tao WanBing-Yang Hu, Tao Wan, Wen-Zhi Zhang, Jia-Hong Dong, Institute and Hospital of Hepatobiliary Surgery, Chinese PLA General Hospital, Beijing 100853, China.
Wen-Zhi ZhangBing-Yang Hu, Tao Wan, Wen-Zhi Zhang, Jia-Hong Dong, Institute and Hospital of Hepatobiliary Surgery, Chinese PLA General Hospital, Beijing 100853, China.
Jia-Hong DongBing-Yang Hu, Tao Wan, Wen-Zhi Zhang, Jia-Hong Dong, Institute and Hospital of Hepatobiliary Surgery, Chinese PLA General Hospital, Beijing 100853, China.
Chinese PLA General Hospital · CNBeijing Tsinghua Chang Gung Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo analyze the risk factors for pancreatic fistula after pancreaticoduodenectomy.

methodsWe conducted a retrospective analysis of 539 successive cases of pancreaticoduodenectomy performed at our hospital from March 2012 to October 2015. Pancreatic fistula was diagnosed in strict accordance with the definition of pancreatic fistula from the International Study Group on Pancreatic Fistula. The risk factors for pancreatic fistula were analyzed by univariate analysis and multivariate logistic regression analysis.

resultsA total of 269 (49.9%) cases of pancreatic fistula occurred after pancreaticoduodenectomy, including 71 (13.17%) cases of grade A pancreatic fistula, 178 (33.02%) cases of grade B, and 20 (3.71%) cases of grade C. Univariate analysis showed no significant correlation between postoperative pancreatic fistula (POPF) and the following factors: age, hypertension, alcohol consumption, smoking, history of upper abdominal surgery, preoperative jaundice management, preoperative bilirubin, preoperative albumin, pancreatic duct drainage, intraoperative blood loss, operative time, intraoperative blood transfusion, Braun anastomosis, and pancreaticoduodenectomy (with or without pylorus preservation). Conversely, a significant correlation was observed between POPF and the following factors: gender (male vs female: 54.23% vs 42.35%, P = 0.008), diabetes (non-diabetic vs diabetic: 51.61% vs 39.19%, P = 0.047), body mass index (BMI) (≤ 25 vs > 25: 46.94% vs 57.82%, P = 0.024), blood glucose level (≤ 6.0 mmol/L vs > 6.0 mmol/L: 54.75% vs 41.14%, P = 0.002), pancreaticojejunal anastomosis technique (pancreatic duct-jejunum double-layer mucosa-to-mucosa pancreaticojejunal anastomosis vs pancreatic-jejunum single-layer mucosa-to-mucosa anastomosis: 57.54% vs 35.46%, P = 0.000), diameter of the pancreatic duct (≤ 3 mm vs > 3 mm: 57.81% vs 38.36%, P = 0.000), and pancreatic texture (soft vs hard: 56.72% vs 29.93%, P = 0.000). Multivariate logistic regression analysis showed that gender (male), BMI > 25, pancreatic duct-jejunum double-layer mucosa-to-mucosa pancreaticojejunal anastomosis, pancreatic duct diameter ≤ 3 mm, and soft pancreas were risk factors for pancreatic fistula after pancreaticoduodenectomy.

conclusionGender (male), BMI > 25, pancreatic duct-jejunum double-layer mucosa-to-mucosa pancreaticojejunal anastomosis, pancreatic duct diameter ≤ 3 mm, and soft pancreas were risk factors for pancreatic fistula after pancreaticoduodenectomy.

Indexed as

AdultAgedAnastomosis, SurgicalBlood Loss, SurgicalBody Mass IndexDiabetes ComplicationsFemaleHumansMaleMiddle AgedMultivariate AnalysisOperative TimePancreasPancreatectomyPancreatic FistulaPancreaticoduodenectomyComplicationsPancreatic ductPancreatic fistulaPancreaticoduodenectomyPancreaticojejunal anastomosis

Identifiers

PMID27678363
PMCPMC5016380
OpenAlexW2510110336

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.