Evidence map›Paper›PMID 27678299›Full record

ArticleThe Journal of urology2017

Nocturnal Polyuria in Older Women with Urge Urinary Incontinence: Role of Sleep Quality, Time in Bed and Medications Used.

Shachi Tyagi, Subashan Perera, Becky D Clarkson, Stasa D Tadic, Neil M Resnick

Abstract read
In one paragraph

Article in The Journal of urology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
  3. Nocturnal polyuria and nocturia.International urology and nephrology · 2023
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Shachi TyagiDivision of Geriatrics and Gerontology, Department of Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania. Electronic address: tyagis@upmc.edu.
Subashan PereraDivision of Geriatrics and Gerontology, Department of Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania.
Becky D ClarksonDivision of Geriatrics and Gerontology, Department of Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania.
Stasa D TadicDivision of Geriatrics and Gerontology, Department of Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania.
Neil M ResnickDivision of Geriatrics and Gerontology, Department of Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania.
University of Pittsburgh · US

Funding

VARIABILITY, STABILITY & SMOOTHNESS OF WALKINGP30AG024827 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Caterina Rosano · 2004 to 2026
$28.6M
Pitt Integrated Clinical and Geroscience Research Training ProgramT32AG021885 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Aditi U Gurkar · 2003 to 2026
$6.7M
Further Enhancing Non-Pharmacological Therapy for IncontinenceR01AG020629 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI RESNICK, NEIL M. · 2003 to 2012
$4.0M
Role of Brain in Bladder Control and Continence in Elderly WomenK23AG031916 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI TADIC, STASA DUSAN · 2008 to 2012
$619k
Long-Term Care Research NetworkK07AG052668 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GREENSPAN, SUSAN L · 2016 to 2020
$439k
Impact of Sleep on Chronobiology of MicturitionR21AG050892 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI TYAGI, SHACHI · 2016 to 2017
$424k
NIA NIH HHS K07 AG052668NIA NIH HHS K23 AG031916NIA NIH HHS P30 AG024827NIA NIH HHS R01 AG020629NIA NIH HHS R21 AG050892NIA NIH HHS T32 AG021885
6 · The paper itself

Abstract

purposeNocturia is common and bothersome in older adults, especially those who are also incontinent. Since nocturnal polyuria is a major contributor, we examined factors associated with nocturnal polyuria in this population to identify those possibly amenable to intervention. MATERIALS AND

methodsWe analyzed baseline data from 2 previously completed studies of urge urinary incontinence. The studies involved 284 women (mean age ± SD 72.9 ± 7.9 years) who also completed 3-day voiding diaries. Participants with a nocturnal polyuria index greater than 33% were categorized as having nocturnal polyuria (nocturnal polyuria index = nocturnal urinary volume per 24-hour urine volume). Associations between nocturnal polyuria and various demographic, clinical and sleep related parameters were determined.

resultsOverall 55% of the participants had nocturnal polyuria. Multivariable regression analysis revealed that age, body mass index, use of angiotensin converting enzyme inhibitor/angiotensin receptor blocker, time spent in bed and duration of first uninterrupted sleep were independent correlates of nocturnal polyuria. Participants with a larger nocturnal excretion reported a shorter duration of uninterrupted sleep before first awakening to void and worse sleep quality despite spending similar time in bed.

conclusionsBody mass index, use of angiotensin converting enzyme inhibitor/angiotensin receptor blockers, time in bed and duration of uninterrupted sleep before first awakening to void are independently associated with nocturnal polyuria in older women with urge urinary incontinence, and are potentially modifiable. These findings also confirm the association between sleep and nocturnal polyuria. Further studies should explore whether interventions to reduce nocturnal polyuria and/or increase the duration of uninterrupted sleep before first awakening to void would help to improve sleep quality in this population and thereby reduce or eliminate the need for sedative hypnotics.

Indexed as

SleepAgedAngiotensin-Converting Enzyme InhibitorsAngiotensin Receptor AntagonistsFemaleHumansMiddle AgedNocturiaPolyuriaRetrospective StudiesRisk FactorsTime FactorsUrinary Incontinence, UrgeAngiotensin-Converting Enzyme InhibitorsAngiotensin Receptor Antagonistsagednocturiapolyuriasleep stages

Identifiers

PMID27678299
PMCPMC5315607
OpenAlexW2521612304

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.