Evidence map›Paper›PMID 27678292›Full record

ReviewCurrent environmental health reports2016

Tungsten: an Emerging Toxicant, Alone or in Combination.

Alicia M Bolt, Koren K Mann

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current environmental health reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 88 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Alicia M BoltLady Davis Institute for Medical Research, Department of Oncology, McGill University, 3755 Côte Ste Catherine Rd, Rm E537, Montréal, Québec, H3T 1E2, Canada.
Koren K MannLady Davis Institute for Medical Research, Department of Oncology, McGill University, 3755 Côte Ste Catherine Rd, Rm E537, Montréal, Québec, H3T 1E2, Canada. koren.mann@mcgill.ca.
McGill University · CA

Funding

CIHR MOP-137149CIHR MOP-142227
6 · The paper itself

Abstract

purpose of reviewTungsten is an emerging environmental toxicant, yet our understanding of the potential risks of exposure on human health is still limited. RECENT

findingsIn this review, we will discuss populations most at risk of exposure to high concentrations of tungsten. In addition, we will highlight what is known about the toxicity profile of tungsten compounds, based on epidemiological, in vitro, and in vivo studies, focusing on bone, immune, pulmonary, and cancer outcomes. Of note, emerging evidence indicates that tungsten can augment the effects of other stimulants, stressors, and toxicants. Of particular importance may be tungsten-cobalt mixtures that seem to be more toxic than either metal alone. This is important because it means that we cannot just evaluate the toxicity of tungsten in isolation. Finally, we still have limited information of how many of the in vitro and in vivo findings translate to human populations, so it will be important to conduct epidemiology studies in highly exposed populations to adequately address the potential risks of tungsten exposure on human health. Together, we discuss recent findings that support further investigation into the toxicities of tungsten alone and in combination with other metals.

Indexed as

CobaltEnvironmental PollutantsHumansOccupational ExposureTungstenTungsten CompoundsCobaltEnvironmental PollutantsTungstenTungsten CompoundsCobaltMetalsToxicityTungstenTungsten carbide

Identifiers

PMID27678292
OpenAlexW2526787741

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.