Evidence map›Paper›PMID 27678170›Full record

ArticleScientific reports2016

Characterization of the Pathogenesis of H10N3, H10N7, and H10N8 Subtype Avian Influenza Viruses Circulating in Ducks.

Miaomiao Zhang, Xingxing Zhang, Kaidi Xu, Qiaoyang Teng, Qinfang Liu, Xuesong Li, Jianmei Yang, Jianqing Xu, Hongjun Chen, Xiaoyan Zhang and 1 more

Erratum issuedAbstract read
In one paragraph

Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

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  7. Review
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  12. A human infection case with avian-origin H10N3 influenza virus.Quantitative imaging in medicine and surgery · 2021
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Miaomiao ZhangShanghai Public Health Clinical Center, Fudan University Shanghai 201508 P. R. China.
Xingxing ZhangShanghai Veterinary Research Institute, Chinese Academic of Agricultural Sciences, Shanghai 200241 P. R. China.
Kaidi XuShanghai Veterinary Research Institute, Chinese Academic of Agricultural Sciences, Shanghai 200241 P. R. China.
Qiaoyang TengShanghai Veterinary Research Institute, Chinese Academic of Agricultural Sciences, Shanghai 200241 P. R. China.
Qinfang LiuShanghai Veterinary Research Institute, Chinese Academic of Agricultural Sciences, Shanghai 200241 P. R. China.
Xuesong LiShanghai Veterinary Research Institute, Chinese Academic of Agricultural Sciences, Shanghai 200241 P. R. China.
Jianmei YangShanghai Veterinary Research Institute, Chinese Academic of Agricultural Sciences, Shanghai 200241 P. R. China.
Jianqing XuShanghai Public Health Clinical Center, Fudan University Shanghai 201508 P. R. China.
Hongjun ChenShanghai Veterinary Research Institute, Chinese Academic of Agricultural Sciences, Shanghai 200241 P. R. China.
Xiaoyan ZhangShanghai Public Health Clinical Center, Fudan University Shanghai 201508 P. R. China.
Zejun LiShanghai Veterinary Research Institute, Chinese Academic of Agricultural Sciences, Shanghai 200241 P. R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Three H10 subtype avian influenza viruses were isolated from domestic ducks in China, designated as SH602/H10N8, FJ1761/H10N3 and SX3180/H10N7, with an intravenous pathogenicity index (IVPI) of 0.39, 1.60, and 1.27, respectively. These H10 viruses showed a complex pathology pattern in different species, although full genome characterizations of the viruses could not identify any molecular determinant underlying the observed phenotypes. Our findings describe the pathobiology of the three H10 subtype AIVs in chickens, ducks, and mice. FJ1761/H10N3 evolved E627K and Q591K substitutions in the gene encoding the PB2 protein in infected mice with severe lung damage, suggesting that H10 subtype avian influenza viruses are a potential threat to mammals.

Identifiers

PMID27678170
PMCPMC5039634

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.