ArticleKidney international2016
Human kidney pericytes produce renin.
Article in Kidney international, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
38 citing papers in PubMed, 56 citations in OpenAlex.
- The endocrine product of renal (preglomerular) contractile pericytes depends on prolyl-4-hydroxylases 2 and 3.The Journal of physiology · 2026Article
- Advances in the Targeted Drug Delivery System for Renal Fibrosis.International journal of nanomedicine · 2026Review
- Pericytes in tissue fibrosis.American journal of physiology. Cell physiology · 2025Review
- Research developments in the neurovascular unit and the blood‑brain barrier (Review).Biomedical reports · 2025Review
- Phosphodiesterase inhibitor ameliorates senescent changes of renal interstitial pericytes in aging kidney.Aging cell · 2024Article
- Low plasma renin activity is associated with "Apparently" idiopathic atrial fibrillation.International journal of cardiology. Heart & vasculature · 2023Article
- Role of perivascular cells in kidney homeostasis, inflammation, repair and fibrosis.Nature reviews. Nephrology · 2023Review
- ZIC1 Dictates Osteogenesis Versus Adipogenesis in Human Mesenchymal Progenitor Cells Via a Hedgehog Dependent Mechanism.Stem cells (Dayton, Ohio) · 2023Article
- Biology of vascular mural cells.Development (Cambridge, England) · 2023Review
- Investigation of heterocellular features of the mouse retinal neurovascular unit by 3D electron microscopy.Journal of anatomy · 2023Article
- A novel renal perivascular mesenchymal cell subset gives rise to fibroblasts distinct from classic myofibroblasts.Scientific reports · 2022Article
- Blood Vessel Resident Human Stem Cells in Health and Disease.Stem cells translational medicine · 2022Review
- Approaches for the isolation and long-term expansion of pericytes from human and animal tissues.Frontiers in cardiovascular medicine · 2022Article
- Cell Hypertrophy: A "Biophysical Roadblock" to Reversing Kidney Injury.Frontiers in cell and developmental biology · 2022Article
- Stem Cell-Based Therapies: What Interventional Radiologists Need to Know.Seminars in interventional radiology · 2021Review
- Aging modulates the effects of ischemic injury upon mesenchymal cells within the renal interstitium and microvasculature.Stem cells translational medicine · 2021Article
- Review
- IFN-I Mediates Lupus Nephritis From the Beginning to Renal Fibrosis.Frontiers in immunology · 2021Review
- Review
- Connexin Signaling in the Juxtaglomerular Apparatus (JGA) of Developing, Postnatal Healthy and Nephrotic Human Kidneys.International journal of molecular sciences · 2020Article
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
Abstract
Pericytes, perivascular cells embedded in the microvascular wall, are crucial for vascular homeostasis. These cells also play diverse roles in tissue development and regeneration as multi-lineage progenitors, immunomodulatory cells and as sources of trophic factors. Here, we establish that pericytes are renin producing cells in the human kidney. Renin was localized by immunohistochemistry in CD146 and NG2 expressing pericytes, surrounding juxtaglomerular and afferent arterioles. Similar to pericytes from other organs, CD146
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.