ArticlePediatric nephrology (Berlin, Germany)2017
Clinical presentation and outcome of pediatric ANCA-associated glomerulonephritis.
Article in Pediatric nephrology (Berlin, Germany), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Renal disease in pediatric rheumatology.Current opinion in rheumatology · 2024Review
- Risk factors for renal outcomes in children with antineutrophil cytoplasmic antibody-associated vasculitis: a nationwide retrospective study in China.World journal of pediatrics : WJP · 2024Article
- Clinical and Renal Histology Findings and Different Responses to Induction Treatment Affecting the Long-Term Renal Outcomes of Children With ANCA-Associated Vasculitis: a Single-Center Cohort Analysis.Frontiers in immunology · 2022Article
- Clinicopathological Analysis of 34 Cases of Primary Antineutrophil Cytoplasmic Antibody-Associated Vasculitis in Chinese Children.Frontiers in pediatrics · 2021Article
- Age-dependent survival in rapidly progressive glomerulonephritis: A nationwide questionnaire survey from children to the elderly.PloS one · 2020Article
- Biologics for childhood systemic vasculitis.Pediatric nephrology (Berlin, Germany) · 2019Review
- Clinical and histopathological prognostic factors affecting the renal outcomes in childhood ANCA-associated vasculitis.Pediatric nephrology (Berlin, Germany) · 2019Article
- Favorable renal outcome in Japanese children with ANCA-associated pauci-immune glomerulonephritis: impact of urine screening program.Pediatric nephrology (Berlin, Germany) · 2017Article
- Favorable renal outcome in Japanese children with ANCA-associated pauci-immune glomerulonephritis: authors' response to comments.Pediatric nephrology (Berlin, Germany) · 2017Article
- Anca-associated crescentic glomerulonephritis in a child with isolated renal involvement.Jornal brasileiro de nefrologiaArticle
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Abstract
backgroundAntineutrophil cytoplasmic antibody (ANCA)-associated vasculitis is a small- and medium-sized vasculitis classically seen in adult patients, with peak onset near the fifth to seventh decade of life. There is little data on ANCA-associated vasculitis in pediatric patients, and most studies have limited follow-up.
methodsThis is a retrospective chart review of 22 patients with ANCA-positive glomerulonephritis in a single institution from 1991 to 2013.
resultsOf the 22 patients, eight (36 %) required renal replacement therapy (RRT) at diagnosis; four of these patients recovered sufficient renal function to initially discontinue dialysis. Five patients (23 %) were treated with plasmapheresis at presentation. The median time from presentation until first clinical or serologic relapse was 1.7 ± 1.2 years. After a median follow-up of 5.8 years, just over half of our patients had chronic kidney disease (CKD) stages 1-3 (55 %). Seven (32 %) patients progressed to end-stage renal disease (ESRD) and eventually required kidney transplant.
conclusionANCA-associated glomerulonephritis is a rare disorder in children. Presentation and outcomes vary significantly among patients. More research is required to follow these patients who are diagnosed in childhood to further characterize the long-term outcome of the disease.
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