ArticleInternational journal of obesity (2005)2016
Trajectories of total and central adiposity throughout adolescence and cardiometabolic factors in early adulthood.
Article in International journal of obesity (2005), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 27 citations in OpenAlex.
- A three-arm randomized controlled trial using ecological momentary intervention, community health workers, and video feedback at family meals to improve child cardiovascular health: the Family Matters study design.BMC public health · 2023Trial
- Adiposity trajectories from ages 11 to 22 years: 1993 Pelotas (Brazil) birth cohort.Cadernos de saude publica · 2026Article
- BMI trajectories from birth to young adulthood associate with distinct cardiometabolic profiles.BMC medicine · 2024Article
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- Trajectories in waist circumference and waist-to-height ratio with left ventricular hypertrophy in childhood.Frontiers in nutrition · 2024Article
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- Waist Circumference Trajectories in Relation to Blood Pressure and the Risk of Hypertension in Chinese Adults.Nutrients · 2022Article
- The Mediation Role of Fatness in Associations between Cardiorespiratory Fitness and Blood Pressure after High-Intensity Interval Training in Adolescents.International journal of environmental research and public health · 2022Article
- Socioeconomic circumstances and lung function growth from early adolescence to early adulthood.Pediatric research · 2021Article
- Revisiting trajectories of BMI in youth: An in-depth analysis of differences between BMI and other adiposity measures.Obesity science & practice · 2021Article
- Do body mass index and waist-to-height ratio over the preceding decade predict retinal microvasculature in 11-12 year olds and midlife adults?International journal of obesity (2005) · 2020Article
- BMI Trajectories from Birth to 23 Years by Cardiometabolic Risks in Young Adulthood.Obesity (Silver Spring, Md.) · 2020Article
- Body mass index trajectories from adolescent to young adult for incident high blood pressure and high plasma glucose.PloS one · 2019Article
- Paediatric obesity and cardiovascular risk factors - A life course approach.Porto biomedical journalReview
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
Abstract
BACKGROUND/
objectivesOur aim was to identify trajectories of total and central adiposity from 13 to 21 years, and to investigate how adiposity changes at different phases of adolescence relate to adulthood cardiovascular risk factors. SUBJECTS/
methodsThis study included participants from a population-based cohort (EPITeen), Portugal. Body mass index (BMI) and waist circumference (WC) were measured at 13, 17 and 21 years, and sex- and age-specific z-scores were calculated. Adiposity trajectories were identified using mixture growth models (BMI, n=2901; WC, n=2898). Cardiovascular risk factors were evaluated at 21 years (n=1763): systolic (SBP) and diastolic blood pressure (DBP), insulin resistance (HOMA-IR), triglycerides and cholesterol. Association of trajectory, and changes in adiposity z-scores with each cardiovascular risk factor was estimated by linear regression models.
results'Normal', 'high, declining' and 'high, increasing' trajectories were identified in both sexes. 'High, increasing' BMI trajectory was associated with less favorable cardiovascular risk profile at 21 years in both sexes, whereas 'high, declining' presented a more favorable profile, similar to 'normal' trajectory in females. In addition, BMI increases between 13-17 years and 17-21 years were associated with increases in systolic and diastolic blood pressure, and insulin resistance, but more strongly for the later period. For every standard deviation (s.d.) increase in BMI between 17-21 years, mean SBP increased by 1.99 mmHg (95% confidence interval (CI): 1.01; 2.97) for females and 3.83 mmHg (2.67; 4.98) for males; the respective increase was 1.56 mmHg (0.72; 2.40) and 2.80 mmHg (1.97; 3.64) for DBP and 0.27 (0.21; 0.32) and 0.30 (0.24; 0.36) for HOMA-IR (log-transformed). Similar results were found for WC.
conclusionsIncreases in adiposity, particularly from late adolescence-to-young adulthood, were associated with unfavorable cardiovascular profile in early adulthood. A benefit on the cardiovascular risk profile for participants in the declining adiposity trajectory was observed.
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