ReviewCellular and molecular life sciences : CMLS2017
Heritability of targeted gene modifications induced by plant-optimized CRISPR systems.
Review in Cellular and molecular life sciences : CMLS, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 53 citations in OpenAlex.
- Gene Flow and Hybridization Potential Between GM/NGT Crops and Conventional Varieties or Wild Relatives: A Scoping Literature Review with Emphasis on Oilseed Rape (Biotech (Basel (Switzerland)) · 2026Review
- Optimization of CRISPR-Cas9 system iniScience · 2024Article
- Unveiling the Genetic Symphony: Harnessing CRISPR-Cas Genome Editing for Effective Insect Pest Management.Plants (Basel, Switzerland) · 2023Review
- CRISPR/Cas9-mediated editing of phytoene desaturase (3 Biotech · 2023Article
- Recent advances in CRISPR-Cas system for the treatment of genetic hearing loss.American journal of stem cells · 2023Review
- CRISPR/Cas9-mediated editing ofFrontiers in plant science · 2023Article
- CRISPR-Based Genome Editing and Its Applications in Woody Plants.International journal of molecular sciences · 2022Review
- Increased mutation efficiency of CRISPR/Cas9 genome editing in banana by optimized construct.PeerJ · 2022Article
- The efficacy of CRISPR-mediated cytosine base editing with the RPS5a promoter in Arabidopsis thaliana.Scientific reports · 2021Article
- Base editing with high efficiency in allotetraploid oilseed rape by A3A-PBE system.Plant biotechnology journal · 2021Article
- Simultaneous TALEN-mediated knockout of chrysanthemum DMC1 genes confers male and female sterility.Scientific reports · 2020Article
- Simplified adenine base editors improve adenine base editing efficiency in rice.Plant biotechnology journal · 2020Article
- Targeted Mutagenesis of the RiceInternational journal of molecular sciences · 2020Article
- Efficient knockout of phytoene desaturase gene using CRISPR/Cas9 in melon.Scientific reports · 2019Article
- Efficient genome editing of Brassica campestris based on the CRISPR/Cas9 system.Molecular genetics and genomics : MGG · 2019Article
- Modern Trends in Plant Genome Editing: An Inclusive Review of the CRISPR/Cas9 Toolbox.International journal of molecular sciences · 2019Review
- Gene editing in plants: progress and challenges.National science review · 2019Article
- Now for the hard ones: is there a limit on CRISPR genome editing in crops?Journal of experimental botany · 2019Article
- Genome Editing in Citrus Tree with CRISPR/Cas9.Methods in molecular biology (Clifton, N.J.) · 2019Article
- A role ofProceedings of the National Academy of Sciences of the United States of America · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The Streptococcus-derived CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats)/Cas9 (CRISPR-associated protein 9) system has emerged as a very powerful tool for targeted gene modifications in many living organisms including plants. Since the first application of this system for plant gene modification in 2013, this RNA-guided DNA endonuclease system has been extensively engineered to meet the requirements of functional genomics and crop trait improvement in a number of plant species. Given its short history, the emphasis of many studies has been the optimization of the technology to improve its reliability and efficiency to generate heritable gene modifications in plants. Here we review and analyze the features of customized CRISPR/Cas9 systems developed for plant genetic studies and crop breeding. We focus on two essential aspects: the heritability of gene modifications induced by CRISPR/Cas9 and the factors affecting its efficiency, and we provide strategies for future design of systems with improved activity and heritability in plants.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.