Evidence map›Paper›PMID 27677365›Full record

ArticleEuropean journal of clinical nutrition2016

Serum hs-CRP varies with dietary cholesterol, but not dietary fatty acid intake in individuals free of any history of cardiovascular disease.

M Mazidi, A Heidari-Bakavoli, S S Khayyatzadeh, M R Azarpazhooh, M Nematy, M Safarian, H Esmaeili, S M R Parizadeh, M Ghayour-Mobarhan, A P Kengne and 1 more

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In one paragraph

Article in European journal of clinical nutrition, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 3 pooled it
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 3 syntheses or guidelines pooled it, 29 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
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  7. Observational
  8. Observational
  9. Review
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  13. Observational
  14. Inflammatory Markers Are Positively Associated with SerumJournal of nutrition and metabolism · 2017
    Article
  15. Food Security and Leukocyte Telomere Length in Adult Americans.Oxidative medicine and cellular longevity · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 4 countries.

M MazidiKey State Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China.
A Heidari-BakavoliCardiovascular Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
S S KhayyatzadehBiochemistry and Nutrition Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
M R AzarpazhoohBiochemistry and Nutrition Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
M NematyBiochemistry and Nutrition Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
M SafarianBiochemistry and Nutrition Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
H EsmaeiliDepartment of Statistics, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
S M R ParizadehBiochemistry and Nutrition Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
M Ghayour-MobarhanBiochemistry and Nutrition Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
A P KengneNon-Communicable Disease Research Unit, South African Medical Research Council and University of Cape Town, Cape Town, South Africa.
G A FernsBrighton & Sussex Medical School, Division of Medical Education, University of Brighton, Brighton, UK.
Mashhad University of Medical Sciences · IRBrighton and Sussex Medical School · GBChinese Academy of Sciences · CNSouth African Medical Research Council · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The objective of this study was to investigate whether serum high-sensitivity C-reactive protein (hs-CRP) concentration varies with dietary fatty acid intake in Iranian adults free of any history of cardiovascular disease (CVD). This cross-sectional study involved 8105 adults (3142 men) aged 35-65 years. Dietary intake was assessed using 24-h dietary recalls. The relationship between anthropometric, cardiometabolic risk factors and dietary data and serum hs-CRP was assessed using SPSS software. Median crude dietary saturated fat decreased across hs-CRP quarters (P =0.009 for linear trend), whereas energy-adjusted total fat (P =0.017), trans-fat (P =0.016), monounsaturated fatty acids (P =0.030) and cholesterol (P =0.005) monotonically increased, with some evidence of statistical interactions by gender. In conclusion, serum hs-CRP concentrations were associated with some components of dietary fatty acid intake in our population of individuals without CVD, suggesting that dietary fat intake could be associated with subclinical inflammation.

Indexed as

AdultAgedCardiovascular DiseasesCholesterol, DietaryC-Reactive ProteinCross-Sectional StudiesDietary FatsEatingFatty AcidsFemaleHumansIranMaleMiddle AgedRisk FactorsCholesterol, DietaryC-Reactive ProteinDietary FatsFatty Acids

Identifiers

PMID27677365
OpenAlexW2525965168

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.