Trial reportAIDS (London, England)2017
Effects of depression and anxiety on antiretroviral therapy adherence among newly diagnosed HIV-infected Chinese MSM.
Trial report in AIDS (London, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 2 syntheses or guidelines pooled it, 59 citations in OpenAlex.
- Prevalence of depression, anxiety and suicide among men who have sex with men in China: a systematic review and meta-analysis.Epidemiology and psychiatric sciences · 2020Pooled it
- Associations Between Anxiety and Adherence to Antiretroviral Medications in Low- and Middle-Income Countries: A Systematic Review and Meta-analysis.AIDS and behavior · 2019Pooled it
- Peer counselling versus standard-of-care on reducing high-risk behaviours among newly diagnosed HIV-positive men who have sex with men in Beijing, China: a randomized intervention study.Journal of the International AIDS Society · 2018Trial
- Longitudinal trends and causal relationships of depression, anxiety, and sleep quality among MSM newly diagnosed with HIV.Social psychiatry and psychiatric epidemiology · 2026Article
- Association of demographics and psychological barriers with late presentation of HIV among men who have sex with men in Chengdu, China.Scientific reports · 2025Article
- The development and validation of the irrational beliefs scale for people living with HIV.BMC public health · 2025Article
- Revealing the complexity of depression configurations in HIV-positive men who have sex with men: a fuzzy-set qualitative comparative analysis.BMC public health · 2025Article
- The Association of Depression, Social Determinants and PrEP Uptake Among Black Sexual Minority Men in the Deep South.Journal of racial and ethnic health disparities · 2024Article
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- Validation of the combined Patient Health Questionnaire Anxiety and Depression Scale among people with HIV in Vietnam.International journal of STD & AIDS · 2023Article
- The Moderating Role of Social Support and HIV Stigma on the Association Between Depression and ART Adherence Among Young Thai Men Who Have Sex with Men.AIDS and behavior · 2023Article
- 'She showed me a new path, a way forward': exploring how navigation influences mental health among Guatemalan gay and bisexual men living with HIV.Health promotion international · 2023Article
- Adherence to Antiretroviral Therapy and Its Predictive Factors Among People Living with HIV in China: A Behavioral Theory-Based Prospective Cohort Study.International journal of behavioral medicine · 2023Article
- Trajectories of depressive symptoms in young and middle-aged men who have sex with men with new HIV-diagnosis: a 1-year prospective cohort study in Beijing, China.Frontiers in public health · 2023Article
- Prevalence and Risks of Depression and Substance Use Among Adults Living with HIV in the Asia-Pacific Region.AIDS and behavior · 2022Article
- Predicting the risk of HIV infection among internal migrant MSM in China: An optimal model based on three variable selection methods.Frontiers in public health · 2022Article
- Poor adherence to highly active antiretroviral therapy and associated factors among people living with HIV in Eastern Ethiopia.SAGE open medicine · 2022Article
- Factors Influencing Clinicians' Willingness to Prescribe Pre-exposure Prophylaxis for Persons at High Risk of HIV in China: Cross-sectional Online Survey Study.JMIR public health and surveillance · 2021Article
- Health-related quality of life of patients with HIV/AIDS at a tertiary care teaching hospital in Ethiopia.Health and quality of life outcomes · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 1 institution in 2 countries.
Funding
Abstract
objectiveOur objective was to explore the effect of depression and anxiety on adherence to antiretroviral therapy (ART) among MSM with newly diagnosed HIV infections.
designWe conducted a prospective study of Chinese MSM with newly diagnosed HIV infections.
methodsThe Hospital Anxiety and Depression Scale was used to measure depression and anxiety at baseline, 6 and 12 months, separately. ART adherence was self-reported once every 3 months ('perfect' or no missing dose in the past 3 months vs. 'imperfect' adherence or at least one missing dose in the past 3 months). We utilized a priori substantial knowledge guided by causal models to identify confounding covariates, and performed mixed-effect logistic regression to assess the effects of depression and anxiety on ART adherence.
resultsWe included 228 participants who initiated ART after HIV diagnosis and before the end of study. A one-unit increase in the depression and anxiety score was associated with a 16% increase [adjusted odds ratio (aOR), 1.16; 95% confidence interval (CI), 1.02-1.32] and a 17% increase (aOR, 1.17; 95% CI, 1.03-1.33) in the odds of reporting imperfect ART adherence, respectively. When depression and anxiety were categorized (normal, borderline, and likely), only likely anxiety had a significant association with imperfect ART adherence (aOR, 4.79; 95% CI, 1.12-20.50).
conclusionDepression and anxiety are risk factors for imperfect ART adherence among Chinese MSM with newly diagnosed HIV infections. Intensive intervention on depression and/or anxiety beyond regular post-HIV-testing counseling may increase adherence to ART, and improve HIV treatment outcomes.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.