Evidence map›Paper›PMID 27676631›Full record

Trial reportMenopause (New York, N.Y.)2017

Trajectories of response to acupuncture for menopausal vasomotor symptoms: the Acupuncture in Menopause study.

Nancy E Avis, Remy R Coeytaux, Beverly Levine, Scott Isom, Timothy Morgan

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Menopause (New York, N.Y.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Nancy E Avis1Department of Social Sciences and Health Policy, Wake Forest School of Medicine, Winston-Salem, NC 2Department of Community and Family Medicine and Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC 3Department of Biostatistical Sciences, Wake Forest School of Medicine, Winston-Salem, NC.
Remy R Coeytaux
Beverly Levine
Scott Isom
Timothy Morgan
Wake Forest University · USClinical Research Institute · US

Funding

Non-specific Effects of Acupuncture in the Treatment of Hot FlashesR01AT005854 · NCCIH · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI AVIS, NANCY E · 2010 to 2014
$2.0M
NCCIH NIH HHS R01 AT005854
6 · The paper itself

Abstract

objectiveTo examine the trajectories of responses to acupuncture treatment for menopausal vasomotor symptoms (VMS) and the characteristics of women in each trajectory.

methodsTwo hundred nine perimenopausal and postmenopausal women aged 45 to 60 years experiencing at least four VMS per day were recruited and randomized to receive up to 20 acupuncture treatments within 6 months or to a waitlist control group. The primary outcome was percent change from baseline in the mean daily VMS frequency. Finite mixture modeling was used to identify patterns of percent change in weekly VMS frequencies over the first 8 weeks. The Freeman-Holton test and analysis of variance were used to compare characteristics of women in different trajectories.

resultsAnalyses revealed four distinct trajectories of change in VMS frequency by week 8 in the acupuncture group. A small group of women (11.6%, n = 19) had an 85% reduction in VMS. The largest group (47%, n = 79) reported a 47% reduction in VMS frequency, 37.3% (n = 65) of the sample showed only a 9.6% reduction in VMS frequency, and a very small group (4.1%, n = 7) had a 100% increase in VMS. Among women in the waitlist control group, 79.5% reported a 10% decrease in VMS frequency at week 8. Baseline number of VMS, number of acupuncture treatments in the first 8 weeks, and traditional Chinese medicine diagnosis were significantly related to trajectory group membership in the acupuncture group.

conclusionsApproximately half of the treated sample reported a decline in VMS frequency, but identifying clear predictors of clinical response to acupuncture treatment of menopausal VMS remains challenging.

Indexed as

PerimenopausePostmenopauseAcupuncture TherapyAutonomic Nervous System DiseasesFemaleHot FlashesHumansMiddle AgedTreatment OutcomeVasomotor System

Identifiers

PMID27676631
PMCPMC5266651
OpenAlexW2526059392

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.