Sleep: How Many Switches Does It Take To Turn Off the Lights?

Michael J Iannacone, David M Raizen

Open access · bronzeAbstract readComment

In one paragraph

Article in Current biology : CB, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it

0cells of the map it votes in

2citing papers in PubMed

–field-weighted citation impact, top 92% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

A Timely Call to Arms: COVID-19, the Circadian Clock, and Critical Care.Journal of biological rhythms · 2021
Review
Stress-Induced Behavioral Quiescence and Abnormal Rest-Activity Rhythms During Critical Illness.Critical care medicine · 2020
Article

4 · The record

Corrections and comments

Comment on
C. elegans Stress-Induced Sleep Emerges from the Collective Action of Multiple Neuropeptides.2016

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Michael J IannaconeDepartment of Neurology and the Center for Sleep and Circadian Neurobiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19014, USA.

David M RaizenDepartment of Neurology and the Center for Sleep and Circadian Neurobiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19014, USA. Electronic address: raizen@mail.med.upenn.edu.

University of Pennsylvania · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sleeping animals do not move or feed and are less responsive. In Caenorhabditis elegans, a single neuron triggers sleep. A recent study shows that the neuron releases several neuropeptides - each with distinct sleep behavioral effects - to promote the collection of behaviors that is sleep.

Indexed as

Caenorhabditis elegansCaenorhabditis elegans ProteinsAnimalsNeuronsNeuropeptidesSleepCaenorhabditis elegans ProteinsNeuropeptides

Identifiers

PMID27676303

DOI10.1016/j.cub.2016.07.051

OpenAlexW2526652967

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.