ArticleJAMA2016
Blood Measurement of Carcinoembryonic Antigen Level for Detecting Recurrence of Colorectal Cancer.
Article in JAMA, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed.
- Serological signatures and pathological features for the management of CEA-negative colorectal cancer: development of combined diagnostic and prognostic nomograms.World journal of surgical oncology · 2026Article
- Prostatic carcinoma with elevated carcinoembryonic antigen: a case report.Frontiers in oncology · 2026Article
- Serum untargeted metabolomics analysis of colorectal cancer.BMC cancer · 2025Article
- Development and validation of an integrative 54 biomarker-based risk identification model for multi-cancer in 42,666 individuals: a population-based prospective study to guide advanced screening strategies.Biomarker research · 2025Article
- Integrative proteomic profiling of tumor and plasma extracellular vesicles identifies a diagnostic biomarker panel for colorectal cancer.Cell reports. Medicine · 2025Article
- Clinical utility of the carcinoembryonic antigen level in patients with stage III colon cancer after surgery and adjuvant chemotherapy.Surgery today · 2024Article
- Article
- Elevated postoperative carcinoembryonic antigen guides adjuvant chemotherapy for stage II colon cancer: a multicentre cohort retrospective study.Scientific reports · 2024Article
- Optimized screening of DNA methylation sites combined with gene expression analysis to identify diagnostic markers of colorectal cancer.BMC cancer · 2023Article
- Surveillance strategies following curative resection and non-operative approach of rectal cancer: How and how long? Review of current recommendations.World journal of gastrointestinal surgery · 2023Review
- Prognostic Value of Combined LMR and CEA Dynamic Monitoring in Postoperative Colorectal Cancer Patients.Journal of inflammation research · 2023Article
- Postoperative circulating tumor DNA testing based on tumor naïve strategy after liver metastasis surgery in colorectal cancer patients.Frontiers in oncology · 2023Article
- FJX1 as a candidate diagnostic and prognostic serum biomarker for colorectal cancer.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2022Article
- Comprehensive Genomic Profiling (CGP)-Informed Personalized Molecular Residual Disease (MRD) Detection: An Exploratory Analysis from the PREDATOR Study of Metastatic Colorectal Cancer (mCRC) Patients Undergoing Surgical Resection.International journal of molecular sciences · 2022Article
- Noninvasive urinary protein signatures associated with colorectal cancer diagnosis and metastasis.Nature communications · 2022Article
- Article
- Detection of Molecular Residual Disease Using Personalized Circulating Tumor DNA Assay in Patients With Colorectal Cancer Undergoing Resection of Metastases.JCO precision oncology · 2021Article
- CEA as a blood-based biomarker in anal cancer.Oncotarget · 2021Article
- Increased AOC1 Expression Promotes Cancer Progression in Colorectal Cancer.Frontiers in oncology · 2021Article
- The Correlation Between Survival Benefit of Preoperative Radiotherapy and Pretreatment Carcinoembryonic Antigen Level in Locally Advanced Rectal Cancer.Frontiers in oncology · 2021Article
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
clinical questionWhat is the trade-off between sensitivity and specificity at specific carcinoembryonic antigen (CEA) thresholds for detecting recurrent colorectal cancer? BOTTOM LINE: To detect colorectal cancer recurrence, the sensitivity of CEA ranges from 68% for a threshold of 10 µg/L to 82% for a threshold of 2.5 µg/L and the specificity ranges from 97% for a threshold of 10 µg/L to 80% for a threshold of 2.5 µg/L.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.