Evidence map›Paper›PMID 27672563›Full record

ArticleIDCases2016

First description of herpes simplex virus type 1 epididymo-orchitis: A new clinical form of herpes simplex virus infection during septic shock?

Dr Mélanie Fromentin, Remy Gauzit, Benoit Gille, Charles Marc Samama

Open access · goldAbstract readCase Reports
In one paragraph

Article in IDCases, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Dr Mélanie FromentinDepartment of Anesthesia and Intensive Care, Cochin University Hospital, Paris Descartes University, 27 Rue du Faubourg Saint Jacques, 75014 Paris, France.
Remy GauzitDepartment of Infectious Diseases, Cochin University Hospital, Paris Descartes University, 27 Rue du Faubourg Saint Jacques, 75014 Paris, France.
Benoit GilleDepartment of Anesthesia and Intensive Care, Cochin University Hospital, Paris Descartes University, 27 Rue du Faubourg Saint Jacques, 75014 Paris, France.
Charles Marc SamamaDepartment of Anesthesia and Intensive Care, Cochin University Hospital, Paris Descartes University, 27 Rue du Faubourg Saint Jacques, 75014 Paris, France.
Université Paris Cité · FRDélégation Paris 5 · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genital herpes is increasingly caused by herpes simplex virus type 1 (HSV-1), but recurrences are less frequent than with HSV-2. Distinguishing between primary genital infection and reactivation can be difficult, but HSV-1 more often causes severe primary infections and fewer recurrences. However, as virus reactivation is common during septic shock, a severe form of HSV-1 reactivation can occur in locations other than the lungs, which remain the most common site. The case of a 79-year-old Caucasian man who presented with HSV-1 epididymo-orchitis after three episodes of severe sepsis or septic shock in the context of acute biliary necrotizing pancreatitis is described. This is the first reported case of HSV-1 epididymo-orchitis due to virus reactivation during sepsis.

Indexed as

CT, computed tomographyELISA, enzyme linked immunosorbent assayEpididymo-orchitisHealth care-associated infectionHerpesviridaeICU, intensive care unitImmunosuppressionNecrotizing pancreatitisPCR, polymerase chain reactionSeptic shockSOFA, sepsis-related organ failure assessment scoreWOPN, walled-off pancreatic necrosis

Identifiers

PMID27672563
PMCPMC5035238
OpenAlexW2477936865

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.