Evidence map›Paper›PMID 27672420›Full record

ArticleOxidative medicine and cellular longevity

Modulatory Effect of 2-(4-Hydroxyphenyl)amino-1,4-naphthoquinone on Endothelial Vasodilation in Rat Aorta.

Javier Palacios, Fredi Cifuentes, Jaime A Valderrama, Julio Benites, David Ríos, Constanza González, Mario Chiong, Benjamín Cartes-Saavedra, Carlos Lafourcade, Ursula Wyneken and 5 more

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 4 countries.

Javier PalaciosDepartamento de Ciencias Químicas y Farmacéuticas, Facultad de Ciencias de la Salud, Universidad Arturo Prat, Iquique, Chile.
Fredi CifuentesExperimental Physiology Laboratory (EPhyL), Instituto Antofagasta, Universidad de Antofagasta, Antofagasta, Chile.
Jaime A ValderramaDepartamento de Ciencias Químicas y Farmacéuticas, Facultad de Ciencias de la Salud, Universidad Arturo Prat, Iquique, Chile.
Julio BenitesDepartamento de Ciencias Químicas y Farmacéuticas, Facultad de Ciencias de la Salud, Universidad Arturo Prat, Iquique, Chile.
David RíosDepartamento de Ciencias Químicas y Farmacéuticas, Facultad de Ciencias de la Salud, Universidad Arturo Prat, Iquique, Chile.
Constanza GonzálezDepartamento de Ciencias Químicas y Farmacéuticas, Facultad de Ciencias de la Salud, Universidad Arturo Prat, Iquique, Chile.
Mario ChiongAdvanced Center for Chronic Diseases, Faculty of Chemical and Pharmaceutical Sciences, University of Chile, Santiago, Chile.ORCID 0000-0002-5174-6545
Benjamín Cartes-SaavedraAdvanced Center for Chronic Diseases, Faculty of Chemical and Pharmaceutical Sciences, University of Chile, Santiago, Chile.
Carlos LafourcadeLaboratorio de Neurociencias, Centro de Investigaciones Biomédicas, Universidad de los Andes, Monseñor Alvaro del Portillo 12.455, 7550000 Santiago, Chile.ORCID 0000-0002-6728-1009
Ursula WynekenLaboratorio de Neurociencias, Centro de Investigaciones Biomédicas, Universidad de los Andes, Monseñor Alvaro del Portillo 12.455, 7550000 Santiago, Chile.
Pamela GonzálezFacultad de Ciencias Biológicas y Centro UC Investigación en Oncología (CITO), Pontificia Universidad Católica de Chile, Chile.
Gareth I OwenFacultad de Ciencias Biológicas y Centro UC Investigación en Oncología (CITO), Pontificia Universidad Católica de Chile, Chile.
Fabián PardoCellular and Molecular Physiology Laboratory (CMPL), Division of Obstetrics and Gynecology, School of Medicine, Faculty of Medicine, Pontificia Universidad Católica de Chile, 8330024 Santiago, Chile.
Luis SobreviaCellular and Molecular Physiology Laboratory (CMPL), Division of Obstetrics and Gynecology, School of Medicine, Faculty of Medicine, Pontificia Universidad Católica de Chile, 8330024 Santiago, Chile; Department of Physiology, Faculty of Pharmacy, Universidad de Sevilla, 41012 Seville, Spain; University of Queensland Centre for Clinical Research (UQCCR), Faculty of Medicine and Biomedical Sciences, University of Queensland, Herston, QLD 4029, Australia.
Pedro Buc CalderonDepartamento de Ciencias Químicas y Farmacéuticas, Facultad de Ciencias de la Salud, Universidad Arturo Prat, Iquique, Chile; Toxicology and Cancer Biology Research Group, Université catholique de Louvain, Brussels, Belgium.ORCID 0000-0003-0483-2624
Arturo Prat University · CLPontificia Universidad Católica de Chile · CLAdvanced Center for Chronic Diseases · CLUniversidad de Los Andes, Chile · CLUniversidad de Antofagasta · CL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The vascular endothelium plays an essential role in the control of the blood flow. Pharmacological agents like quinone (menadione) at various doses modulate this process in a variety of ways. In this study,

Identifiers

PMID27672420
PMCPMC5031853
OpenAlexW2517673408

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.