Evidence map›Paper›PMID 27672239›Full record

ArticleJournal of substance abuse treatment2016

Opioid Overdose Experience, Risk Behaviors, and Knowledge in Drug Users from a Rural versus an Urban Setting.

Kelly E Dunn, Frederick S Barrett, Claudia Yepez-Laubach, Andrew C Meyer, Bryce J Hruska, Kathy Petrush, Suzan Berman, Stacey C Sigmon, Michael Fingerhood, George E Bigelow

Abstract read
In one paragraph

Article in Journal of substance abuse treatment, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Kelly E DunnJohns Hopkins University School of Medicine, Behavioral Pharmacology Research Unit, Department of Psychiatry and Behavioral Sciences.
Frederick S BarrettJohns Hopkins University School of Medicine, Behavioral Pharmacology Research Unit, Department of Psychiatry and Behavioral Sciences.
Claudia Yepez-LaubachJohns Hopkins University School of Medicine, Behavioral Pharmacology Research Unit, Department of Psychiatry and Behavioral Sciences.
Andrew C MeyerUniversity of Vermont, Department of Psychiatry.
Bryce J HruskaUniversity of Vermont, Department of Psychiatry.
Kathy PetrushJohns Hopkins University School of Medicine, Behavioral Pharmacology Research Unit, Department of Medicine.
Suzan BermanJohns Hopkins University School of Medicine, Behavioral Pharmacology Research Unit, Department of Medicine.
Stacey C SigmonUniversity of Vermont, Department of Psychiatry; University of Vermont, Department of Psychology.
Michael FingerhoodJohns Hopkins University School of Medicine, Behavioral Pharmacology Research Unit, Department of Medicine.
George E BigelowJohns Hopkins University School of Medicine, Behavioral Pharmacology Research Unit, Department of Psychiatry and Behavioral Sciences.

Funding

HUMAN BEHAVIORAL PHARMACOLOGY OF SUBSTANCE ABUSET32DA007209 · NIDA · JOHNS HOPKINS UNIVERSITY · PI Eric C. Strain, Elise M Weerts · 1985 to 2026
$12.9M
Using Cannabinoids to Enhance Opioid Analgesic Effects in HumansR01DA040644 · NIDA · JOHNS HOPKINS UNIVERSITY · PI CAMPBELL, CLAUDIA MICHELLE, DUNN, KELLY E · 2016 to 2021
$3.4M
A118G SNP and OPRM1 Gene Opioid-Mediated Effects in HumansR01DA035246 · NIDA · JOHNS HOPKINS UNIVERSITY · PI DUNN, KELLY E · 2014 to 2018
$3.2M
Interim Treatment: Leveraging buprenophine + technology to bridge waitlist delaysR34DA037385 · NIDA · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI SIGMON, STACEY C · 2014 to 2015
$652k
Development and Validation of a Computerized Opioid Overdose InterventionR21DA035327 · NIDA · JOHNS HOPKINS UNIVERSITY · PI DUNN, KELLY E · 2013 to 2014
$446k
NIDA NIH HHS L30 DA029942NIDA NIH HHS R01 DA035246NIDA NIH HHS R01 DA040644NIDA NIH HHS R21 DA035327NIDA NIH HHS R34 DA037385NIDA NIH HHS T32 DA007209
6 · The paper itself

Abstract

backgroundOpioid use is highly prevalent in the United States and there has been an increased incidence in the rate of opioid-related overdose. While evidence suggests there are substantial differences in opioid use among rural versus urban settings, the rate of overdose and corresponding frequency of opioid overdose risk behaviors and overdose knowledge between rural and urban settings have not been examined.

methodsIndividuals with opioid use disorder from rural (N=98) and urban (N=247) settings completed a self-report survey regarding their lifetime history of overdose and overdose risk behaviors. Participants also completed the Brief Opioid Overdose Knowledge (BOOK) questionnaire, a 12-item self-report measure of opioid overdose knowledge.

resultsOverall, 35.6% of participants had experienced an overdose, and prevalence of overdose was significantly higher (p<.01) among rural (45.9%) vs. urban (31.6%) participants, though fewer rural participants reported past 30-day risk behaviors. There were few differences observed between the subset of rural and urban participants who had experienced an overdose, and fewer rural participants with a history of overdose reported past 30-day risk behaviors. Both rural and urban participants performed poorly on the BOOK, though the percent of correct responses was lowest among rural participants with a history of overdose.

conclusionResults demonstrate higher rates of overdose among rural opioid users, though rural participants were less likely to report recent risk behaviors. Results also suggest that knowledge regarding key factors related to opioid overdose is severely lacking, particularly among rural opioid users, which could be a potential target for future intervention efforts.

Indexed as

AdultAnalgesics, OpioidDrug OverdoseDrug UsersFemaleHealth Knowledge, Attitudes, PracticeHumansMaleOpioid-Related DisordersRisk-TakingRural PopulationSurveys and QuestionnairesUnited StatesUrban PopulationAnalgesics, OpioidBOOKnaloxoneopioidopioid overdoseopioid use disorder

Identifiers

PMID27672239
PMCPMC5034762

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.