Evidence map›Paper›PMID 27672204›Full record

ArticleThe American journal of tropical medicine and hygiene2016

West Nile Virus Infection in Human and Mouse Cornea Tissue.

Bradley J Blitvich, Tian Wang, Vandana Saxena, Shemin Zeng, Karen M Harmon, Matthew D Raymond, Kenneth M Goins, Cynthia R Reed, Robert F Mullins, Mark A Greiner

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Bradley J BlitvichDepartment of Veterinary Microbiology and Preventive Medicine, College of Veterinary Medicine, Iowa State University, Ames, Iowa.
Tian WangDepartment of Microbiology and Immunology, University of Texas Medical Branch, Galveston, Texas.
Vandana SaxenaDepartment of Microbiology and Immunology, University of Texas Medical Branch, Galveston, Texas.
Shemin ZengDepartment of Ophthalmology and Visual Sciences, Carver College of Medicine, University of Iowa, Iowa City, Iowa.
Karen M HarmonDepartment of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, Iowa.
Matthew D RaymondDepartment of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, Iowa.
Kenneth M GoinsDepartment of Ophthalmology and Visual Sciences, Carver College of Medicine, University of Iowa, Iowa City, Iowa.
Cynthia R ReedIowa Lions Eye Bank, Coralville, Iowa.
Robert F MullinsDepartment of Ophthalmology and Visual Sciences, Carver College of Medicine, University of Iowa, Iowa City, Iowa.
Mark A GreinerDepartment of Ophthalmology and Visual Sciences, Carver College of Medicine, University of Iowa, Iowa City, Iowa. mark-greiner@uiowa.edu.

Funding

Phenotypic characterization of T’Ho virus and the development of tools for its serologic diagnosisR03AI167042 · NIAID · IOWA STATE UNIVERSITY · PI BLITVICH, BRADLEY J · 2022 to 2023
$153k
NIAID NIH HHS R03 AI167042
6 · The paper itself

Abstract

The purpose of this study was to determine the in vitro and ex vivo susceptibility of human corneal cells to West Nile virus (WNV) infection and evaluate the ability of the virus to disseminate to the corneas of infected mice. Human corneal epithelial cells were challenged with WNV, incubated for 1-6 days, and tested for evidence of WNV infection. Viral RNA and antigen were detected at every time point, and the virus reached a peak titer of 2.5 × 10

Indexed as

AnimalsCell LineCorneaHumansMiceMice, Inbred C57BLRNA, ViralWest Nile FeverWest Nile virusRNA, Viral

Identifiers

PMID27672204
PMCPMC5094237

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.