ArticleTravel medicine and infectious disease
Predictors of MERS-CoV infection: A large case control study of patients presenting with ILI at a MERS-CoV referral hospital in Saudi Arabia.
Article in Travel medicine and infectious disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.
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Who cites it
28 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Comparison of confirmed COVID-19 with SARS and MERS cases - Clinical characteristics, laboratory findings, radiographic signs and outcomes: A systematic review and meta-analysis.Reviews in medical virology · 2020Pooled it
- MERS transmission and risk factors: a systematic review.BMC public health · 2018Pooled it
- Liver dysfunction on admission worsens clinical manifestations and outcomes of coronavirus disease 2019.Chinese medical journal pulmonary and critical care medicine · 2023Article
- Potential Treatment of COVID-19 with Traditional Chinese Medicine: What Herbs Can Help Win the Battle with SARS-CoV-2?Engineering (Beijing, China) · 2022Review
- Human Body Performance with COVID-19 Affectation According to Virus Specification Based on Biosensor Techniques.Sensors (Basel, Switzerland) · 2021Review
- MERS-CoV Confirmation among 6,873 suspected persons and relevant Epidemiologic and Clinical Features, Saudi Arabia - 2014 to 2019.EClinicalMedicine · 2021Article
- Where we missed? Middle East Respiratory Syndrome (MERS-CoV) epidemiology in Saudi Arabia; 2012-2019.The Science of the total environment · 2020Article
- Middle East Respiratory Syndrome (MERS) and novel coronavirus disease-2019 (COVID-19): From causes to preventions in Saudi Arabia.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2020Review
- The costs of an expanded screening criteria for COVID-19: A modelling study.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2020Article
- Middle East Respiratory Syndrome Coronavirus and Severe Acute Respiratory Syndrome Coronavirus.Seminars in respiratory and critical care medicine · 2020Review
- Longitudinal hematologic and immunologic variations associated with the progression of COVID-19 patients in China.The Journal of allergy and clinical immunology · 2020Article
- Focus on Middle East respiratory syndrome coronavirus (MERS-CoV).Medecine et maladies infectieuses · 2020Review
- Demographic Variations of MERS-CoV Infection among Suspected and Confirmed Cases: An Epidemiological Analysis of Laboratory-Based Data from Riyadh Regional Laboratory.BioMed research international · 2020Article
- A database of geopositioned Middle East Respiratory Syndrome Coronavirus occurrences.Scientific data · 2019Article
- Middle East respiratory syndrome coronavirus in pediatrics: a report of seven cases from Saudi Arabia.Frontiers of medicine · 2019Article
- Epidemiological status of the Middle East respiratory syndrome coronavirus in 2019: an update from January 1 to March 31, 2019.International journal of general medicine · 2019Article
- Evaluation of visual triage for screening of Middle East respiratory syndrome coronavirus patients.New microbes and new infections · 2018Article
- Development of a risk-prediction model for Middle East respiratory syndrome coronavirus infection in dialysis patients.Hemodialysis international. International Symposium on Home Hemodialysis · 2018Article
- Factors associated with recovery delay in a sample of patients diagnosed by MERS-CoV rRT-PCR: A Saudi Arabian multicenter retrospective study.Influenza and other respiratory viruses · 2018Article
- Middle East respiratory syndrome coronavirus: risk factors and determinants of primary, household, and nosocomial transmission.The Lancet. Infectious diseases · 2018Review
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Authors and funding
12 authors.
Funding
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Abstract
backgroundA case control study to better characterize the clinical features, laboratory, and radiological abnormalities associated with MERS-CoV infection in order to help with early identification of this syndrome from other respiratory infections.
methodsEighty patients admitted to a hospital in Riyadh, diagnosed with MERS-CoV infection based on RT-PCR were matched on age, sex, and the presence of a co-morbid condition on a basis of 1:2 to other patients admitted with respiratory symptoms and tested negative for MERS-CoV on RT-PCR.
resultsNone of the reported MERS-CoV presenting symptoms was significantly associated with being infected with MERS-CoV. On the other hand, WBC count was significantly lower in patients with confirmed MERS-CoV infection (median 5.7 vs 9.3, P: 0.0004). Neutrophil count was as well significantly lower in MERS-CoV patients (median 3.7 vs 6.7, P: 0.0001). Both AST, and ALT values were significantly higher in MERS-CoV infected group (AST median 42 vs 36, P: 0.03, and ALT median 33 vs 28, P: 0.003). Overall our MERS-CoV mortality rate was (10%) below the national figure of (40%).
conclusionsNone of the presenting symptoms are specific for MERS-CoV infection. And out of all the investigations WBC, neutrophil counts, AST and ALT values have some predictive utility.
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