Observational studyJournal of diabetes and its complications2017
Visit-to-visit systolic blood pressure variability and microvascular complications among patients with diabetes.
Observational study in Journal of diabetes and its complications, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- American Association of Clinical Endocrinology Clinical Practice Guideline: Developing a Diabetes Mellitus Comprehensive Care Plan-2022 Update.Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists · 2022Guideline
- Visit-to-visit blood pressure variability and risk of chronic kidney disease: A systematic review and meta-analyses.PloS one · 2020Pooled it
- Effect of angiotensin II receptor blocker and salt supplementation on short-term blood pressure variability in type 2 diabetes.Journal of human hypertension · 2020Trial
- Systolic Blood Pressure Variability and Outcomes in Atrial Fibrillation: A Nationwide Population Study in Korea.Journal of Korean medical science · 2026Article
- Research progress on the correlation between blood pressure variability and hypertensive microvascular disease.Frontiers in cardiovascular medicine · 2026Review
- Blood pressure variability is associated with the occurrence of diabetic microangiopathy in type 2 diabetes mellitus: a cross-sectional study.European journal of medical research · 2025Article
- Visit-to-visit variability of blood pressure and risk of diabetic retinopathy: a systematic review and meta-analysis.American journal of cardiovascular disease · 2024Article
- Association of blood pressure with incident diabetic microvascular complications among diabetic patients: Longitudinal findings from the UK Biobank.Journal of global health · 2023Article
- The Impact of Systolic Blood Pressure, Pulse Pressure, and Their Variability on Diabetes Retinopathy among Patients with Type 2 Diabetes.Journal of diabetes research · 2022Article
- Prognostic importance of visit-to-visit blood pressure variability for micro- and macrovascular outcomes in patients with type 2 diabetes: The Rio de Janeiro Type 2 Diabetes Cohort Study.Cardiovascular diabetology · 2020Observational
- Retrospective cohort study of the relationship between systolic blood pressure variability and multiple sclerosis disability.BMJ open · 2020Article
- Association of Visit-to-Visit Variability of Blood Pressure with Cardiovascular Disease among Type 2 Diabetes Mellitus Patients: A Cohort Study.Diabetes & metabolism journal · 2019Article
- Increasing SBP variability is associated with an increased risk of developing incident diabetic foot ulcers.Journal of hypertension · 2018Article
- Blood Pressure Variability and Autonomic Dysfunction.Current diabetes reports · 2018Review
- Article
- Periodic microstructures of blood capillaries revealed by synchrotron X-ray multi-resolution microscopic analysis.Biomedical optics express · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
aimsTo examine the relationship between systolic blood pressure (SBP) variability and the risk of microvascular complications in a non-elderly diabetic population.
methodsThis is a retrospective cohort study of individuals aged ≤60years treated for diabetes in 2003 in the US Department of Veterans Affairs healthcare system. Individuals were followed for five years for any new diagnosis of diabetic nephropathy, retinopathy, or neuropathy. In each year of follow-up, individuals were classified into quartiles based on their SBP variability.
resultsWe identified 208,338 patients with diabetes without diabetic nephropathy, retinopathy, or neuropathy at baseline. Compared to individuals with the least SBP variability (Quartile 1), those with most variability (Quartile 4) had 81% (OR=1.81; 95% CI, 1.72-1.91), 17% (OR=1.17; 95% CI, 1.13-1.21), 30% (OR=1.30; 95% CI, 1.25-1.35), and 19% (OR=1.19; 95% CI, 1.15-1.23) higher incidence of nephropathy, retinopathy, neuropathy, and any complication, respectively, after adjusting for mean SBP, demographic and clinical factors.
conclusionsWe found a significant graded relationship between SBP variability and the incidence of each complication and of any combined endpoint. This is the first study showing a significant association between SBP variability and the risk of diabetic retinopathy and neuropathy.
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