ArticleInternational journal of psychophysiology : official journal of the International Organization of Psychophysiology2017
Evidence of a prominent genetic basis for associations between psychoneurometric traits and common mental disorders.
Article in International journal of psychophysiology : official journal of the International Organization of Psychophysiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed.
- Distinct Event-Related-Potential Biomarkers of Broad Versus Specific Dimensions of the Hierarchical Taxonomy of Psychopathology Externalizing Spectrum.Clinical psychological science : a journal of the Association for Psychological Science · 2026Article
- Opposing Relations of Reward Positivity with Anhedonia and Threat Sensitivity: Implications for Differential Dimensional Diagnosis.Clinical psychological science : a journal of the Association for Psychological Science · 2025Article
- Electrodermal reactivity in an aversive countdown task: Concurrent and prospective relations with triarchic psychopathy traits and antisocial behavior outcomes in a child-aged sample.Frontiers in psychiatry · 2025Article
- Examining associations between genetic and neural risk for externalizing behaviors in adolescence and early adulthood.Psychological medicine · 2024Article
- Assessing general versus specific liability for externalizing problems in adolescence: Concurrent and prospective prediction of symptoms of conduct disorder, ADHD, and substance use.Journal of psychopathology and clinical science · 2022Article
- The Genetic and Neural Substrates of Externalizing Behavior.Biological psychiatry global open science · 2022Article
- Linking RDoC and HiTOP: A new interface for advancing psychiatric nosology and neuroscience.Clinical psychology review · 2021Review
- Quantifying Dispositional Fear as Threat Sensitivity: Development and Initial Validation of a Model-Based Scale Measure.Assessment · 2020Article
- Neurobiology and the Hierarchical Taxonomy of Psychopathology: progress toward ontogenetically informed and clinically useful nosology .Dialogues in clinical neuroscience · 2020Review
- Using a co-twin control design to evaluate alternative trait measures as indices of liability for substance use disorders.International journal of psychophysiology : official journal of the International Organization of Psychophysiology · 2020Article
- Social Problems in Children: Exploring the Contribution of Triarchic Traits and Parenting.Child psychiatry and human development · 2020Article
- Highs and lows: Genetic susceptibility to daily events.PloS one · 2020Article
- Toward a multimodal measurement model for the neurobehavioral trait of affiliative capacity.Personality neuroscience · 2020Article
- Methodological Advances in Leveraging Neuroimaging Datasets in Adolescent Substance Use Research.Current addiction reports · 2019Article
- Comparing the Triarchic and Five-Factor Trait Models: Relations With Psychopathy and Other Clinical Criteria in an Incarcerated Offender Sample.Journal of personality disorders · 2019Article
- Incorporating neurophysiological measures into clinical assessments: Fundamental challenges and a strategy for addressing them.Psychological assessment · 2019Review
- Interrelations Among Biologically Relevant Personality Traits, Emotion Regulation Strategies, and Clinical Symptoms.Journal of psychopathology and behavioral assessment · 2019Article
- Disinhibition as a unifying construct in understanding how personality dispositions undergird psychopathology.Journal of research in personality · 2019Article
- Article
- Distress intolerance modulation of neurophysiological markers of cognitive control during a complex go/no-go task.Journal of abnormal psychology · 2018Article
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9 authors.
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Abstract
Threat sensitivity (THT) and weak inhibitory control (or disinhibition; DIS) are trait constructs that relate to multiple types of psychopathology and can be assessed psychoneurometrically (i.e., using self-report and physiological indicators combined). However, to establish that psychoneurometric assessments of THT and DIS index biologically-based liabilities, it is important to clarify the etiologic bases of these variables and their associations with clinical problems. The current work addressed this important issue using data from a sample of identical and fraternal adult twins (N=454). THT was quantified using a scale measure and three physiological indicators of emotional reactivity to visual aversive stimuli. DIS was operationalized using scores on two scale measures combined with two brain indicators from cognitive processing tasks. THT and DIS operationalized in these ways both showed appreciable heritability (0.45, 0.68), and genetic variance in these traits accounted for most of their phenotypic associations with fear, distress, and substance use disorder symptoms. Our findings suggest that, as indices of basic dispositional liabilities for multiple forms of psychopathology with direct links to neurophysiology, psychoneurometric assessments of THT and DIS represent novel and important targets for biologically-oriented research on psychopathology.
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