Evidence map›Paper›PMID 27671479›Full record

ArticleAIDS and behavior2017

Understanding Patterns of Social Support and Their Relationship to an ART Adherence Intervention Among Adults in Rural Southwestern Uganda.

Esther C Atukunda, Angella Musiimenta, Nicholas Musinguzi, Monique A Wyatt, Justus Ashaba, Norma C Ware, Jessica E Haberer

Registry-linked trialAbstract read
In one paragraph

Article in AIDS and behavior, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05656287 (My Mobile Wallet), which is not on this map. Cited by 41 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05656287 naunknown statusnot on this mapstarted 2022, after this paper: background citation

My Mobile Wallet: An Intervention to Support Access to Tuberculosis Care and Medication Adherence in Rural Uganda

TypeinterventionalSponsorMbarara University of Science and TechnologyRan2022 to 2026Enrolled242ConditionsTuberculosisArmsSMS texts + incentives + Wisepill device for medication monitoring, SMS texts only + Wisepill device for medication monitoring, Wisepill device for medication monitoring only
3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Esther C AtukundaGlobal Health Collaborative, Mbarara University of Science and Technology, Mbarara, Uganda. estheratukunda@gmail.com.
Angella MusiimentaGlobal Health Collaborative, Mbarara University of Science and Technology, Mbarara, Uganda.
Nicholas MusinguziGlobal Health Collaborative, Mbarara University of Science and Technology, Mbarara, Uganda.
Monique A WyattGlobal Health and Social Medicine, Harvard Medical School, Boston, MA, USA.
Justus AshabaGlobal Health Collaborative, Mbarara University of Science and Technology, Mbarara, Uganda.
Norma C WareGlobal Health and Social Medicine, Harvard Medical School, Boston, MA, USA.
Jessica E HabererMassachusetts General Hospital, Center for Global Health, Boston, MA, USA.

Funding

Mbarara University Research Training Initiative (MURTI)D43TW010128 · FIC · MBARARA UNIVERSITY/SCIENCE/ TECHNOLOGY · PI OBUA, CELESTINO · 2015 to 2019
$3.5M
Development of Real-Time Antiretroviral Therapy Adherence Intervention in UgandaR34MH100940 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI HABERER, JESSICA ELIZABETH · 2013 to 2015
$593k
FIC NIH HHS D43 TW010128NIMH NIH HHS R34 MH100940
6 · The paper itself

Abstract

SMS is a widely used technology globally and may also improve ART adherence, yet SMS notifications to social supporters following real-time detection of missed doses showed no clear benefit in a recent pilot trial. We examine the demographic and social-cultural dynamics that may explain this finding. In the trial, 63 HIV-positive individuals initiating ART received a real-time adherence monitor and were randomized to two types of SMS reminder interventions versus a control (no SMS). SMS notifications were also sent to 45 patient-identified social supporters for sustained adherence lapses. Like participants, social supporters were interviewed at enrollment, following their matched participant's adherence lapse and at exit. Social supporters with regular income (RR = 0.27, P = 0.001) were significantly associated with fewer adherence lapses. Instrumental support was associated with fewer adherence lapses only among social supporters who were food secure (RR = 0.58, P = 0.003). Qualitative interview data revealed diverse and complex economic and relationship dynamics, affecting social support. Resource availability in emotionally positive relationships seemingly facilitated helpful support, while limited resources prevented active provision of support for many. Effective social support appeared subject to social supporters' food security, economic stability and a well-functioning social network dependent on trust and supportive disclosure.

Indexed as

Medication AdherenceSocial SupportAdultAnti-HIV AgentsDisclosureFemaleHIV InfectionsHumansMaleMiddle AgedPilot ProjectsRandomized Controlled Trials as TopicRural PopulationText MessagingUgandaAnti-HIV AgentsAdherenceARTRelation dynamicsSocial supportUganda

Identifiers

PMID27671479
PMCPMC5288444

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.