Evidence map›Paper›PMID 27671475›Full record

ArticleMolecular psychiatry2017

Transgenerational disruption of functional 5-HT

F Razoux, H Russig, T Mueggler, C Baltes, K Dikaiou, M Rudin, I M Mansuy

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular psychiatry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
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  5. Review
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  8. Review
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  11. The future of rodent models in depression research.Nature reviews. Neuroscience · 2019
    Review
  12. Article
  13. Review
  14. Article
  15. The adaptive brain in mental health: overcoming inherited risk factors.Journal of psychiatry & neuroscience : JPN · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

F RazouxLaboratory of Neuroepigenetics, University and ETH Zurich, Brain Research Institute, Center for Neuroscience Zürich, Zurich, Switzerland.
H RussigLaboratory of Neuroepigenetics, University and ETH Zurich, Brain Research Institute, Center for Neuroscience Zürich, Zurich, Switzerland.
T MuegglerInstitute for Biomedical Engineering, University and ETH Zurich, Zurich, Switzerland.
C BaltesInstitute for Biomedical Engineering, University and ETH Zurich, Zurich, Switzerland.
K DikaiouInstitute for Biomedical Engineering, University and ETH Zurich, Zurich, Switzerland.
M RudinInstitute for Biomedical Engineering, University and ETH Zurich, Zurich, Switzerland.
I M MansuyLaboratory of Neuroepigenetics, University and ETH Zurich, Brain Research Institute, Center for Neuroscience Zürich, Zurich, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Traumatic stress in early life is a strong risk factor for psychiatric disorders that can affect individuals across several generations. Although the underlying mechanisms have been proposed to implicate serotonergic transmission in the brain, the neural circuits involved remain poorly delineated. Using pharmacological functional magnetic resonance imaging in mice, we demonstrate that traumatic stress in postnatal life alters 5-HT

Indexed as

AdultAnimalsBrainBrain MappingConnectomeFamily CharacteristicsHumansMental DisordersMiceNeural PathwaysNeurobiologyReceptor, Serotonin, 5-HT1AStress, PsychologicalReceptor, Serotonin, 5-HT1A

Identifiers

PMID27671475

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.