Evidence map›Paper›PMID 27671326›Full record

ReviewAdvances in therapy2016

Hip Osteoarthritis: Etiopathogenesis and Implications for Management.

Nicholas J Murphy, Jillian P Eyles, David J Hunter

3 registry-linked trialsAbstract readReview
In one paragraph

Review in Advances in therapy, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 126 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
126citing papers in PubMed, 8 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04018690 naunknown statusnot on this mapstarted 2019, after this paper: background citation

Project Arthritis Recovering Quality of Life Through Education - Hip

TypeinterventionalSponsorUniversity of Sao Paulo General HospitalRan2019 to 2020Enrolled48ConditionsHip OsteoarthritisArmsPatients will be submitted to needle lavage, followed by the injection of 3mL of hylan and 1 mL of ropivacaine, Patients will be submitted to needle lavage, followed by the injection of 0,5mL triamcinolone (10mg) and 1 mL of ropivacaine,
NCT07147491 phase4recruitingnot on this mapstarted 2025, after this paper: background citation

Study to Verify the Effectiveness and Safety of the Electrically Powered Orthopedic Exercise Device on Gait Ability in Patients Who Have Undergone Hip Surgery: Investigator-Initiated, Single-Center, Single-Group Clinical Trial

TypeinterventionalSponsorYonsei UniversityRan2025 to 2026Enrolled30ConditionsHip SurgeryArmsElectrically Powered Orthopedic Exercise Device
NCT07147530 phase4recruitingnot on this mapstarted 2025, after this paper: background citation

Study to Verify Effectiveness and Safety of the Electrically Powered Orthopedic Exercise Device on Gait Ability in Patients With Hip Joint Diseases: Investigator Initiated, Single Center, Single Group Clinical Trial

TypeinterventionalSponsorYonsei UniversityRan2025 to 2026Enrolled30ConditionsHip DiseaseArmsElectrically Powered Orthopedic Exercise Device
3 · Its place in the literature

Who cites it

126 citing papers in PubMed, 8 syntheses or guidelines pooled it.

  1. Pooled it
  2. Management of hip osteoarthritis: harnessing the potential of mesenchymal stem cells-a systematic review.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2024
    Pooled it
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  5. Antithrombotic prophylaxis following total hip arthroplasty: a level I Bayesian network meta-analysis.Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology · 2024
    Pooled it
  6. Pooled it
  7. Intra-Articular Viscosupplementation for Patients with Hip Osteoarthritis: A Meta-Analysis and Systematic Review.Medical science monitor : international medical journal of experimental and clinical research · 2019
    Pooled it
  8. Pooled it
  9. Effects of Sanqi Shengyu External Application Cream and Pulsed Electromagnetic Field on Knee Osteoarthritis in Older Adults: A Randomized Controlled Trial.Physiotherapy research international : the journal for researchers and clinicians in physical therapy · 2026
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66 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Nicholas J MurphyDepartment of Rheumatology, Royal North Shore Hospital and Northern Clinical School, University of Sydney, Reserve Road, St Leonards, Sydney, NSW, 2065, Australia.
Jillian P EylesDepartment of Rheumatology, Royal North Shore Hospital and Northern Clinical School, University of Sydney, Reserve Road, St Leonards, Sydney, NSW, 2065, Australia.
David J HunterDepartment of Rheumatology, Royal North Shore Hospital and Northern Clinical School, University of Sydney, Reserve Road, St Leonards, Sydney, NSW, 2065, Australia. David.Hunter@sydney.edu.au.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Highly prevalent among the elderly, hip osteoarthritis (OA) carries a heavy burden of disease. Guidelines for the management of hip OA are often extrapolated from knee OA research, despite clear differences in the etiopathogenesis and response to treatments of OA at these sites. We propose that hip OA requires specific attention separate from other OA phenotypes. Our understanding of the etiopathogenesis of hip OA has seen significant advance over the last 15 years, since Ganz and colleagues proposed femoroacetabular impingement (FAI) as an important etiological factor. This narrative review summarizes the current understanding of the etiopathogenesis of hip OA and identifies areas requiring further research. Therapeutic approaches for hip OA are considered in light of the condition's etiopathogenesis. The evidence for currently adopted management strategies is considered, especially those approaches that may have disease-modifying potential. We propose that shifting the focus of hip OA research and public health intervention to primary prevention and early detection may greatly improve the current management paradigm.

Indexed as

Hip JointOsteoarthritis, HipAgedDisease ManagementFemoracetabular ImpingementHumansEtiologyFAIFemoroacetabular impingementHipManagementOsteoarthritisRheumatologyRisk factorsTherapy

Identifiers

PMID27671326
PMCPMC5083776

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.