Evidence map›Paper›PMID 27670931›Full record

ArticleGene expression patterns : GEP2016

Expression of the insulinoma-associated 1 (insm1) gene in Xenopus laevis tadpole retina and brain.

Jennifer L Bosse, Heithem M El-Hodiri

Open access · hybridAbstract read
In one paragraph

Article in Gene expression patterns : GEP, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Jennifer L BosseGraduate Program in Molecular, Cellular, and Developmental Biology, College of Biological Sciences, Ohio State University, Columbus, OH, USA.
Heithem M El-HodiriGraduate Program in Molecular, Cellular, and Developmental Biology, College of Biological Sciences, Ohio State University, Columbus, OH, USA; Center for Molecular and Human Genetics, The Research Institute at Nationwide Children's Hospital, Columbus, OH, USA; Department of Pediatrics, College of Medicine, Ohio State University, Columbus, OH, USA. Electronic address: Heithem.El-Hodiri@NationwideChildrens.org.
Nationwide Children's Hospital · USThe Ohio State University · US

Funding

The Role of Rx in Retinal Progenitor Cell DevelopmentR01EY015480 · NEI · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · PI EL-HODIRI, HEITHEM M · 2004 to 2015
$3.7M
NEI NIH HHS R01 EY015480
6 · The paper itself

Abstract

The insulinoma-associated 1 (insm1) gene is involved in the differentiation of several neuronal and endoderm derived cell types. insm1 is expressed in the retina and brain of several vertebrates including Xenopus laevis. We report the detailed expression pattern of insm1 in the X. laevis tadpole retina and brain. X. laevis insm1 is expressed in most of the ciliary marginal zone of the mature retina and the optic tectum, dorsal pallium, hypothalamus and preoptic areas of the developing tadpole brain. Overall, insm1 is expressed in regions of the tadpole brain and retina harboring populations of progenitor cells.

Indexed as

AnimalsBrainGene Expression Regulation, DevelopmentalLarvaRetinaStem CellsTranscription FactorsXenopus laevisXenopus ProteinsINSM1 protein, XenopusTranscription FactorsXenopus ProteinsCiliary marginal zoneDorsal palliumHypothalamusinsm1Optic tectumXenopus laevis

Identifiers

PMID27670931
PMCPMC5114149
OpenAlexW2523714070

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.