ArticleBritish journal of clinical pharmacology2017
A multifaceted intervention to reduce drug-related complications in surgical patients.
Article in British journal of clinical pharmacology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.
- Effectiveness of interventions on the appropriate use of opioids for noncancer pain among hospital inpatients: A systematic review.British journal of clinical pharmacology · 2020Pooled it
- Trial
- Medication discrepancies identified by medication reconciliation among patients with acute coronary syndrome.Naunyn-Schmiedeberg's archives of pharmacology · 2024Observational
- Introducing a pharmacist-led transmural care program to reduce drug-related problems in orthogeriatric patients: a prospective interventional study.BMC geriatrics · 2024Article
- Surgical Pharmacy for Optimizing Medication Therapy Management Services within Enhanced Recovery after Surgery (ERASJournal of clinical medicine · 2023Review
- Bedside check of medication appropriateness (BED-CMA) as a risk-based tool for bedside clinical pharmacy services: A proof-of-concept study at the trauma surgery ward.Computational and structural biotechnology journal · 2023Article
- Positive Patient Postoperative Outcomes with Pharmacotherapy: A Narrative Review including Perioperative-Specialty Pharmacist Interviews.Journal of clinical medicine · 2022Article
- Systematic Review of Risk Factors Assessed in Predictive Scoring Tools for Drug-Related Problems in Inpatients.Journal of clinical medicine · 2022Review
- Impact of Pharmacist-Directed Medication Reconciliation in Reducing Medication Discrepancies: A Randomized Controlled Trial.The Canadian journal of hospital pharmacy · 2022Article
- Drug-related problems and determinants among elective surgical patients: A prospective observational study.SAGE open medicine · 2022Article
- The pharmacotherapy team: A novel strategy to improve appropriate in-hospital prescribing using a participatory intervention action method.British journal of clinical pharmacology · 2021Article
- Interventions to deprescribe potentially inappropriate medications in the elderly: Lost in translation?Journal of clinical pharmacy and therapeutics · 2020Review
- External validation of a clinical pharmacy intervention in geriatric inpatients: a controlled study.International journal of clinical pharmacy · 2019Article
- A multifaceted intervention to reduce guideline non-adherence among prescribing physicians in Dutch hospitals.International journal of clinical pharmacy · 2017Article
- A multifaceted intervention to reduce drug-related complications in surgical patients.British journal of clinical pharmacology · 2017Article
Corrections and comments
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Authors and funding
10 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimThe P-REVIEW study was a prospective, multicenter, open intervention study, designed to determine whether a multifaceted intervention of educating the prescriber combined with medication review and pharmaceutical visits to the ward by the hospital pharmacist could lead to a reduction in drug-related complications among surgical patients.
methodsA total of 6780 admissions of 5940 patients to surgical, urological and orthopaedic wards during the usual care period and 6484 admissions of 5711 patients during the intervention period were included. An educational programme covering pain management, antithrombotics, fluid and electrolyte management, prescription in case of renal insufficiency and antibiotics was developed. National and local hospital guidelines were included. Hospital pharmacists performed medication safety consultations, combining medication review of high-risk patients and a visit to the physician on the ward.
resultsA significantly lower proportion of admissions with one or more clinically relevant, potentially preventable, drug-related problems (including death, temporary or sustained disability, increased length of hospital stay or readmission within 30 days) occurred in the intervention period (1.1% (73/6484) compared to the usual care period [1.6% (106/6780)] (P = 0.029). The relative risk (RR) was 0.72 (95% CI 0.53-0.97). Several types of drug-related problems occurred less frequently. Costs incurred as result of time spent on study-related activities were not different before and after the intervention.
conclusionsThe P-REVIEW study shows that education and support of the prescribing physician with respect to high-risk patients in surgical departments leads to a significant, clinically relevant benefit for patients without generating additional costs.
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