Evidence map›Paper›PMID 27670795›Full record

Trial reportThe American journal of cardiology2016

Magnetic Resonance Venous Volume Measurements in Peripheral Artery Disease (from ELIMIT).

Hassan Kamran, Vijay Nambi, Smita Negi, Eric Y Yang, Changyi Chen, Salim S Virani, Panos Kougias, Alan B Lumsden, Joel D Morrisett, Christie M Ballantyne and 1 more

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in The American journal of cardiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Trial
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  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Hassan KamranDivision of Atherosclerosis and Vascular Medicine, Department of Medicine, Baylor College of Medicine, Houston, Texas.
Vijay NambiMichael E DeBakey VA Medical Center, Houston, Texas; Division of Atherosclerosis and Vascular Medicine, Department of Medicine, Baylor College of Medicine, Houston, Texas; Methodist DeBakey Heart and Vascular Center, Houston Methodist Hospital, Houston, Texas.
Smita NegiWashington Hospital Center, Georgetown University, Washington, District of Columbia.
Eric Y YangDivision of Atherosclerosis and Vascular Medicine, Department of Medicine, Baylor College of Medicine, Houston, Texas; Methodist DeBakey Heart and Vascular Center, Houston Methodist Hospital, Houston, Texas.
Changyi ChenMichael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, Texas.
Salim S ViraniMichael E DeBakey VA Medical Center, Houston, Texas; Division of Atherosclerosis and Vascular Medicine, Department of Medicine, Baylor College of Medicine, Houston, Texas.
Panos KougiasMichael E DeBakey VA Medical Center, Houston, Texas.
Alan B LumsdenMethodist DeBakey Heart and Vascular Center, Houston Methodist Hospital, Houston, Texas.
Joel D MorrisettDivision of Atherosclerosis and Vascular Medicine, Department of Medicine, Baylor College of Medicine, Houston, Texas.
Christie M BallantyneDivision of Atherosclerosis and Vascular Medicine, Department of Medicine, Baylor College of Medicine, Houston, Texas; Methodist DeBakey Heart and Vascular Center, Houston Methodist Hospital, Houston, Texas.
Gerd BrunnerDivision of Atherosclerosis and Vascular Medicine, Department of Medicine, Baylor College of Medicine, Houston, Texas; Methodist DeBakey Heart and Vascular Center, Houston Methodist Hospital, Houston, Texas. Electronic address: gbrunner@bcm.edu.
Baylor College of Medicine · USHouston Methodist · USGeorgetown University · USMichael E. DeBakey VA Medical Center · US

Funding

Effect of lipid modification on peripheral arterial disease (PAD)R01HL075824 · NHLBI · BAYLOR COLLEGE OF MEDICINE · PI BALLANTYNE, CHRISTIE MITCHELL · 2003 to 2007
$4.4M
Proteolysis of ultralarge von Willebrand factor and metabolic syndrome-diabetesR01HL085769 · NHLBI · BLOODWORKS · PI DONG, JING-FEI · 2008 to 2011
$1.5M
LESION QUANTIFICATION IN HUMAN CAROTID ATHEROSCLEROSISR01HL063090 · NHLBI · BAYLOR COLLEGE OF MEDICINE · PI MORRISETT, JOEL DAVID · 2002 to 2005
$1.3M
Microvascular Perfusion Assessment of Ischemic Diabetic Ulcers Using MRIK25HL121149 · NHLBI · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI BRUNNER, GERD · 2015 to 2019
$799k
NHLBI NIH HHS K25 HL121149NHLBI NIH HHS R01 HL063090NHLBI NIH HHS R01 HL075824NHLBI NIH HHS R01 HL085769
6 · The paper itself

Abstract

The relation between the arterial and venous systems in patients with impaired lower extremity blood flow remains poorly described. The objective of this secondary analysis of the Effectiveness of Intensive Lipid Modification Medication in Preventing the Progression on Peripheral Artery Disease Trial was to determine the association between femoral vein (FV) volumes and measurements of peripheral artery disease. FV wall, lumen, and total volumes were quantified with fast spin-echo proton density-weighted magnetic resonance imaging scans in 79 patients with peripheral artery disease over 2 years. Reproducibility was excellent for FV total vessel (intraclass correlation coefficient 0.924, confidence interval 0.910 to 0.935) and lumen volumes (intraclass correlation coefficient 0.893, confidence interval 0.873 to 0.910). Baseline superficial femoral artery volumes were directly associated with FV wall (r = 0.46, p <0.0001), lumen (r = 0.42, p = 0.0001), and total volumes (r = 0.46, p <0.0001). The 2-year change in maximum walking time was inversely associated with the 24-month change in FV total volume (r = -0.45, p = 0.03). In conclusion, FV volumes can be measured reliably with fast spin-echo proton density-weighted magnetic resonance imaging, and baseline superficial femoral artery plaque burden is positively associated with FV volumes, whereas the 2-year change in FV volumes and leg function show an inverse relation.

Indexed as

Blood VolumeDouble-Blind MethodFemaleFemoral VeinHumansLegMagnetic Resonance ImagingMaleMiddle AgedPeripheral Arterial DiseaseReproducibility of ResultsRisk FactorsWalk Test

Identifiers

PMID27670795
PMCPMC5179037
OpenAlexW2515212573

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.