ArticleThe journal of headache and pain2016
Altered functional connectivity of the marginal division in migraine: a resting-state fMRI study.
Article in The journal of headache and pain, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.
- Headache-related circuits and high frequencies evaluated by EEG, MRI, PET as potential biomarkers to differentiate chronic and episodic migraine: Evidence from a systematic review.The journal of headache and pain · 2022Pooled it
- Structural and functional brain changes in perimenopausal women who are susceptible to migraine: a study protocol of multi-modal MRI trial.BMC medical imaging · 2018Trial
- Volumetric analysis of hippocampal subregions in migraine without aura: an exploratory study on mechanisms underlying migraine chronification.The journal of headache and pain · 2025Article
- Advances of neuroimaging findings in medication overuse headache.Frontiers in neuroscience · 2025Review
- Altered cerebral neurovascular coupling in medication-overuse headache: A study combining multi-modal resting-state fMRI with 3D PCASL.Frontiers in neuroscience · 2023Article
- Hypoperfusion in nucleus accumbens in chronic migraine using 3D pseudo-continuous arterial spin labeling imaging MRI.The journal of headache and pain · 2022Article
- Abnormalities in resting-state EEG microstates are a vulnerability marker of migraine.The journal of headache and pain · 2022Article
- Altered local and distant functional connectivity density in chronic migraine: a resting-state functional MRI study.Neuroradiology · 2021Article
- Structural brain network characteristics in patients with episodic and chronic migraine.The journal of headache and pain · 2021Article
- The Instant Effects of Continuous Transcutaneous Auricular Vagus Nerve Stimulation at Acupoints on the Functional Connectivity of Amygdala in Migraine without Aura: A Preliminary Study.Neural plasticity · 2020Article
- Functional connectivity studies in migraine: what have we learned?The journal of headache and pain · 2019Review
- Volume Gain of Brainstem on Medication-Overuse Headache Using Voxel-Based Morphometry.Chinese medical journal · 2018Article
- Molecular and functional PET-fMRI measures of placebo analgesia in episodic migraine: Preliminary findings.NeuroImage. Clinical · 2018Article
- Altered functional connectivity architecture of the brain in medication overuse headache using resting state fMRI.The journal of headache and pain · 2017Article
- Brain networking analysis in migraine with and without aura.The journal of headache and pain · 2017Article
- Volume expansion of periaqueductal gray in episodic migraine: a pilot MRI structural imaging study.The journal of headache and pain · 2017Article
- Nonspecific periaqueductal gray lesions on T2WI in episodic migraine.The journal of headache and pain · 2016Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe marginal division of neostriatum (MrD) is a flat, pan-shaped zone between the neostriatum and the globus pallidus, and previous documents demonstrated that it was involved in the modulation of pain. The aim of this study is to investigate the roles of the MrD of the human brain in the chronicization migraine using resting state functional magnetic resonance imaging (rs-fMRI).
methodsConventional MRI, 3D structure images, and rs-fMRI were performed in 18 patients with episodic migraines (EM), 16 patients with chronic migraine (CM), 44 patients with medication overuse headache plus chronic migraine (MOH + CM), and 32 normal controls (NC). MrD was defined using manual delineation on structural images, and was selected as the seed to calculate the functional connectivity (FC).
resultsCompared with the NC group, the decreased FC of MrD was observed in the EM and CM groups, and increased FC of MrD was demonstrated in all patient groups. Compared with the EM group, the decreased FC of MrD was revealed in the CM and MOH + CM groups, and the increased FC occurred only in the CM group. Increased FC of MrD alone was observed in the MOH + CM group compared with that in the CM group.
conclusionThis study confirmed the double neuromodulation network of MrD in pain modulation and migraine chronicization; however, the mechanism requires further investigation.
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