Evidence map›Paper›PMID 27670411›Full record

ArticlePhysiological reports2016

Inhibition of alveolar Na transport and LPS causes hypoxemia and pulmonary arterial vasoconstriction in ventilated rats.

Bodo Davieds, Julian Gross, Marc M Berger, Emel Baloğlu, Peter Bärtsch, Heimo Mairbäurl

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Physiological reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Bodo DaviedsMedical Clinic VII, Sports Medicine, University of Heidelberg, Heidelberg, Germany.
Julian GrossMedical Clinic VII, Sports Medicine, University of Heidelberg, Heidelberg, Germany.
Marc M BergerDepartment of Anesthesiology, Perioperative and General Critical Care Medicine Salzburg General Hospital Paracelsus Medical University, Salzburg, Austria.
Emel BaloğluMedical Clinic VII, Sports Medicine, University of Heidelberg, Heidelberg, Germany Translational Lung Research Center Heidelberg (TLRC-H), Member of the German Center for Lung Research (DZL), Heidelberg, Germany Department of Pharmacology, Acibadem University, Istanbul, Turkey.
Peter BärtschMedical Clinic VII, Sports Medicine, University of Heidelberg, Heidelberg, Germany.
Heimo MairbäurlMedical Clinic VII, Sports Medicine, University of Heidelberg, Heidelberg, Germany Translational Lung Research Center Heidelberg (TLRC-H), Member of the German Center for Lung Research (DZL), Heidelberg, Germany heimo.mairbaeurl@med.uni-heidelberg.de.
Heidelberg University · DEGerman Center for Lung Research · DEParacelsus Medical University · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oxygen diffusion across the alveolar wall is compromised by low alveolar oxygen but also by pulmonary edema, and leads to hypoxemia and hypoxic pulmonary vasoconstriction (HPV). To test, whether inhibition of alveolar fluid reabsorption results in an increased pulmonary arterial pressure and whether this effect enhances HPV, we established a model, where anesthetized rats were ventilated with normoxic (21% O

Indexed as

Alveolar reabsorptionamiloridehypoxiainflammationpulmonary edemapulmonary vascular resistance

Identifiers

PMID27670411
PMCPMC5037927
OpenAlexW2524444926

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.