Evidence map›Paper›PMID 27670409›Full record

ArticlePhysiological reports2016

Plasminogen activator inhibitor-1 does not contribute to the pulmonary pathology induced by acute exposure to ozone.

Hamza S Elkhidir, Jeremy B Richards, Kevin R Cromar, Cynthia S Bell, Roger E Price, Constance L Atkins, Chantal Y Spencer, Farhan Malik, Amy L Alexander, Katherine J Cockerill and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Physiological reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Specialized Pro-Resolving Lipid Mediators Regulate Ozone-Induced Pulmonary and Systemic Inflammation.Toxicological sciences : an official journal of the Society of Toxicology · 2018
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Hamza S ElkhidirDivision of Critical Care Medicine, Department of Pediatrics, McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, Texas.
Jeremy B RichardsDivision of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, College of Medicine, Medical University of South Carolina, Charleston, South Carolina.
Kevin R CromarDepartment of Environmental Medicine, New York University School of Medicine, Tuxedo, New York.
Cynthia S BellDivision of Nephrology, Department of Pediatrics, McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, Texas.
Roger E PriceComparative Pathology Laboratory, Center for Comparative Medicine, Baylor College of Medicine, Houston, Texas.
Constance L AtkinsDivision of Pulmonary Medicine, Department of Pediatrics, McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, Texas.
Chantal Y SpencerSection of Pediatric Pulmonology, Department of Pediatrics, Baylor College of Medicine, Houston, Texas.
Farhan MalikDivision of Critical Care Medicine, Department of Pediatrics, McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, Texas.
Amy L AlexanderPediatric Research Center, Department of Pediatrics, McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, Texas.
Katherine J CockerillPediatric Research Center, Department of Pediatrics, McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, Texas.
Ikram U HaqueDivision of Critical Care Medicine, Department of Pediatrics, McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, Texas.
Richard A JohnstonDivision of Critical Care Medicine, Department of Pediatrics, McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, Texas Pediatric Research Center, Department of Pediatrics, McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, Texas Department of Integrative Biology and Pharmacology, McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, Texas richard.a.johnston@uth.tmc.edu.
The University of Texas Health Science Center at Houston · USBaylor College of Medicine · USThe University of Texas Health Science Center · USMedical University of South Carolina · USNew York University · US

Funding

Visfatin and Ozone-Induced Airway Hyperresponsiveness in ObesityR03ES024883 · NIEHS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI JOHNSTON, RICHARD ALAN · 2015 to 2016
$154k
Obesity and Allergic Airway HyperresponsivenessR03AI107432 · NIAID · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI JOHNSTON, RICHARD ALAN · 2013 to 2014
$152k
Obesity and Environmental Lung Disease: The Role of ChemerinR03ES022378 · NIEHS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI JOHNSTON, RICHARD ALAN · 2013 to 2014
$151k
NIAID NIH HHS R03 AI107432NIEHS NIH HHS R03 ES022378NIEHS NIH HHS R03 ES024883
6 · The paper itself

Abstract

Expression of plasminogen activator inhibitor (PAI)-1, the major physiological inhibitor of fibrinolysis, is increased in the lung following inhalation of ozone (O

Indexed as

Airway hyperresponsivenessepithelial celllung injurymacrophage inflammatory protein‐2neutrophil

Identifiers

PMID27670409
PMCPMC5037925
OpenAlexW2525524677

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.