Evidence map›Paper›PMID 27669828›Full record

ArticleLeukemia & lymphoma2017

Weight change trends and overall survival in United States veterans with follicular lymphoma treated with chemotherapy.

Daphne Y Xiao, Suhong Luo, Katiuscia O'Brian, Weijian Liu, Kenneth R Carson

Open access · greenAbstract read
In one paragraph

Article in Leukemia & lymphoma, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Evaluation of skeletal muscle indicators following allogeneic hematopoietic stem cell transplantation: verification of skeletal muscle mass adjustment.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Observational
  3. Impact of body weight changes on adverse events and treatment outcomes during R-CHOP chemotherapy for non-Hodgkin's lymphoma.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Daphne Y Xiaoa Research Service , St. Louis Veterans Affairs Medical Center , St. Louis , MO , USA.
Suhong Luoa Research Service , St. Louis Veterans Affairs Medical Center , St. Louis , MO , USA.
Katiuscia O'Briana Research Service , St. Louis Veterans Affairs Medical Center , St. Louis , MO , USA.
Weijian Liua Research Service , St. Louis Veterans Affairs Medical Center , St. Louis , MO , USA.
Kenneth R Carsona Research Service , St. Louis Veterans Affairs Medical Center , St. Louis , MO , USA.
Washington University in St. Louis · USSaint Louis University · US

Funding

Washington University Institute of Clinical and Translational SciencesUL1TR000448 · NCATS · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2012 to 2016
$41.4M
Worksite Policies and neighborhood Influences on Obesity and Cancer RiskU54CA155496 · NCI · WASHINGTON UNIVERSITY · PI COLDITZ, GRAHAM A. · 2011 to 2016
$9.0M
CLINICAL HEMATOLOGY RESEARCH CAREER DEVELOPMENT PROGRAM AT WASHINGTON UNIVERSITYK12HL087107 · NHLBI · WASHINGTON UNIVERSITY · PI SADLER, J EVAN · 2006 to 2016
$3.8M
Washington University Institute of Clinical and Translational SciencesTL1TR000449 · NCATS · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2012 to 2016
$2.5M
NCATS NIH HHS TL1 TR000449NCATS NIH HHS UL1 TR000448NCI NIH HHS U54 CA155496NHLBI NIH HHS K12 HL087107
6 · The paper itself

Abstract

Understanding weight change patterns in follicular lymphoma (FL) may be important for the assessment of prognosis as well as the long-term care of survivors. A retrospective cohort of United States veterans with a new diagnosis of FL between October 1, 1998 and September 30, 2010 was assembled. Weight changes were evaluated before, during, and after treatment in 896 FL patients who received cyclophosphamide, doxorubicin, vincristine, and prednisone, with or without rituximab (CHOP ± R); cyclophosphamide, vincristine, and prednisone, with or without rituximab (CVP ± R); or rituximab monotherapy. Weight decreased an average of 1.4 kg during therapy, and >5% weight loss during this time period was associated with worse overall survival. Weight increased to an average of 1.4 kg above baseline by 24 months after treatment initiation, with 15% gaining greater than 10% of their baseline weight. Weight management strategies may be an important part of long-term survivorship planning.

Indexed as

Body WeightVeteransAdultAgedAntineoplastic Combined Chemotherapy ProtocolsBiomarkersBody Mass IndexFemaleHumansLymphoma, FollicularMaleMiddle AgedMortalityNeoplasm StagingProportional Hazards ModelsSurvival AnalysisBiomarkersBody weight changeslymphomaveterans

Identifiers

PMID27669828
PMCPMC5428550
OpenAlexW2524706387

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.