Evidence map›Paper›PMID 27669320›Full record

ArticleBiosensors2016

Rapid, Portable, Multiplexed Detection of Bacterial Pathogens Directly from Clinical Sample Matrices.

Christopher R Phaneuf, Betty Mangadu, Matthew E Piccini, Anup K Singh, Chung-Yan Koh

Abstract read
In one paragraph

Article in Biosensors, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Christopher R PhaneufBiotechnology and Bioengineering, Sandia National Laboratories, Livermore, CA 94551, USA. crphane@sandia.gov.
Betty MangaduBiotechnology and Bioengineering, Sandia National Laboratories, Livermore, CA 94551, USA. bmangad@sandia.gov.
Matthew E PicciniBiotechnology and Bioengineering, Sandia National Laboratories, Livermore, CA 94551, USA. mpcostabile@msn.com.
Anup K SinghBiotechnology and Bioengineering, Sandia National Laboratories, Livermore, CA 94551, USA. aksingh@sandia.gov.
Chung-Yan KohBiotechnology and Bioengineering, Sandia National Laboratories, Livermore, CA 94551, USA. ckoh@sandia.gov.

Funding

Microfluidic Platform for Multiplexed DiagnosticsR01AI098853 · NIAID · SANDIA CORP-SANDIA NATIONAL LABORATORIES · PI SINGH, ANUP K. · 2012 to 2015
$3.5M
NIAID NIH HHS R01 AI098853
6 · The paper itself

Abstract

Enteric and diarrheal diseases are a major cause of childhood illness and death in countries with developing economies. Each year, more than half of a million children under the age of five die from these diseases. We have developed a portable, microfluidic platform capable of simultaneous, multiplexed detection of several of the bacterial pathogens that cause these diseases. This platform can perform fast, sensitive immunoassays directly from relevant, complex clinical matrices such as stool without extensive sample cleanup or preparation. Using only 1 µL of sample per assay, we demonstrate simultaneous multiplexed detection of four bacterial pathogens implicated in diarrheal and enteric diseases in less than 20 min.

Indexed as

ImmunoassayMicrofluidicsPoint-of-Care SystemsAnimalsBacterial InfectionsHumansReproducibility of ResultsSensitivity and Specificitycentrifugaldiagnosticsenteric diseasesimmunoassaymicrofluidicspathogen detectionpoint-of-care

Identifiers

PMID27669320
PMCPMC5192369

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.