Evidence map›Paper›PMID 27669319›Full record

ArticleJournal of clinical medicine2016

Platypnea-Orthodeoxia Syndrome: Multiple Pathophysiological Interpretations of a Clinical Picture Primarily Consisting of Orthostatic Dyspnea.

Renato De Vecchis, Cesare Baldi, Carmelina Ariano

RetractedAbstract readRetracted Publication
In one paragraph

Article in Journal of clinical medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Severe Pneumonia Caused by SARS-CoV-2: A Novel Cause of Platypnoea-Orthodeoxia Syndrome.European journal of case reports in internal medicine · 2022
    Article
  7. Article
  8. Article
  9. Article
  10. COVID-19: New disease, new manifestations.Archivos de bronconeumologia · 2020
    Article
  11. Article
  12. Article
  13. Article
  14. Positional cyanosis reveals platypnea-orthodeoxia-syndrome.Respiratory medicine case reports · 2019
    Article
  15. Article
  16. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Renato De VecchisCardiology Unit, Presidio Sanitario Intermedio "Elena d'Aosta", ASL Napoli 1 Centro, 80137 Napoli, Italy. devecchis.erre@virgilio.it.
Cesare BaldiHeart Department, Interventional Cardiology, Azienda Ospedaliero-Universitaria "San Giovanni di Dio e Ruggi d'Aragona", 84131 Salerno, Italy. giovenale80@gmail.com.
Carmelina ArianoCardiology Unit, Presidio Sanitario Intermedio "Elena d'Aosta", ASL Napoli 1 Centro, 80137 Napoli, Italy. carmelariano@tiscali.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Platypnea-orthodexia syndrome (POS) is often a challenging diagnostic problem. It is characterized by dyspnea that is accentuated by standing or sitting positions due to a marked fall in blood oxygen saturation, and instead is improved by assuming the lying position. In the present brief review, the authors address the pathophysiology of POS, and outline its clinical symptoms as well as the main modalities of diagnostic evaluation and possible therapeutic options. Moreover, some problems concerning much-debated issues and persistent uncertainties about the pathophysiology of POS are presented along with the description of the diagnostic and therapeutic resources currently available for this syndrome.

Indexed as

intracardiac shuntsplatypneapulmonary arteriovenous shuntsventilation/perfusion mismatch

Identifiers

PMID27669319
PMCPMC5086587

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.