Evidence map›Paper›PMID 27669206›Full record

ReviewMolecules (Basel, Switzerland)2016

Anti-Inflammatory Activity of Citrus bergamia Derivatives: Where Do We Stand?

Nadia Ferlazzo, Santa Cirmi, Gioacchino Calapai, Elvira Ventura-Spagnolo, Sebastiano Gangemi, Michele Navarra

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed.

  1. Trial
  2. Review
  3. Bergamot (Food science & nutrition · 2026
    Review
  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Anti-Inflammatory Effects of (3Pharmaceuticals (Basel, Switzerland) · 2022
    Article
  13. Review
  14. Article
  15. The Second Life ofMolecules (Basel, Switzerland) · 2021
    Review
  16. Review
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nadia FerlazzoDepartment of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Messina I-98168, Italy. nadiaferlazzo@email.it.
Santa CirmiDepartment of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Messina I-98168, Italy. scirmi@unime.it.
Gioacchino CalapaiDepartment of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, Messina I-98125, Italy. gcalapai@unime.it.
Elvira Ventura-SpagnoloDepartment of Biotechnology and Legal Medicine, University of Palermo, Palermo I-90127, Italy. elvira.ventura@unipa.it.
Sebastiano GangemiDepartment of Clinical and Experimental Medicine, University of Messina, Messina I-98125, Italy. gangemis@unime.it.
Michele NavarraDepartment of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Messina I-98168, Italy. mnavarra@unime.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammatory diseases affect a large portion of the worldwide population, and chronic inflammation is a major risk factor for several dangerous pathologies. To limit the side effects of both synthetic and biological anti-inflammatory drugs, the use of herbal medicines, nutraceuticals and food supplements has increased tremendously as alternative and/or complementary medicine to treat several pathologies, including inflammation. During the last decades, the biological properties of Citrus bergamia (bergamot) derivatives have obtained important scientific achievements, and it has been suggested their use in a context of a multitarget pharmacological strategy. Here, we present an overview of the anti-inflammatory properties of bergamot extracts that could represent the scientific basis for develop novel and alternative strategies to improve health status and attenuate inflammatory conditions.

Indexed as

Anti-Inflammatory AgentsCitrusHerbal MedicineHumansInflammationPlant ExtractsAnti-Inflammatory AgentsPlant Extractsantioxidant activitybergamotCitrus bergamiacomplementary and alternative medicinesflavonoidsinflammationnatural products

Identifiers

PMID27669206
PMCPMC6274179

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.