Evidence map›Paper›PMID 27668945›Full record

ArticleAging2016

Cell cycle controls stress response and longevity in

Matthias Dottermusch, Theresa Lakner, Tobias Peyman, Marinella Klein, Gerd Walz, Elke Neumann-Haefelin

Open access · greenAbstract read
In one paragraph

Article in Aging, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. The NDR family of kinases: essential regulators of aging.Frontiers in molecular neuroscience · 2024
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Matthias DottermuschDepartment of Medicine IV, Medical Center, Faculty of Medicine, University of Freiburg, Germany.
Theresa LaknerDepartment of Medicine IV, Medical Center, Faculty of Medicine, University of Freiburg, Germany.
Tobias PeymanDepartment of Medicine IV, Medical Center, Faculty of Medicine, University of Freiburg, Germany.
Marinella KleinDepartment of Medicine IV, Medical Center, Faculty of Medicine, University of Freiburg, Germany.
Gerd WalzDepartment of Medicine IV, Medical Center, Faculty of Medicine, University of Freiburg, Germany.
Elke Neumann-HaefelinDepartment of Medicine IV, Medical Center, Faculty of Medicine, University of Freiburg, Germany.
University of Freiburg · DE

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5M
NIH HHS P40 OD010440
6 · The paper itself

Abstract

Recent studies have revealed a variety of genes and mechanisms that influence the rate of aging progression. In this study, we identified cell cycle factors as potent regulators of health and longevity in

Indexed as

AnimalsCaenorhabditis elegansCaenorhabditis elegans ProteinsCell CycleCyclin-Dependent Kinase 2Cyclin EDNA-Binding ProteinsGene ExpressionLongevityStress, PhysiologicalTranscription FactorsCaenorhabditis elegans ProteinsCyclin-Dependent Kinase 2Cyclin EDNA-Binding Proteinsskn-1 protein, C elegansTranscription FactorsagingC. eleganscell cycleDAF-16/FOXOgermlineSKN-1/Nrf

Identifiers

PMID27668945
PMCPMC5076454
OpenAlexW2527048361

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.