Evidence map›Paper›PMID 27668755›Full record

ReviewCurrent opinion in neurobiology2016

Olfactory circuits and behaviors of nematodes.

Sophie Rengarajan, Elissa A Hallem

Abstract readReview
In one paragraph

Review in Current opinion in neurobiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Article
  2. Article
  3. Efficacy of 2-undecanol produced byMicrobiology spectrum · 2025
    Article
  4. Article
  5. Article
  6. Induced knockdown ofHeliyon · 2024
    Article
  7. Review
  8. Article
  9. Review
  10. AWA and ASH Homologous Sensing Genes ofPathogens (Basel, Switzerland) · 2022
    Article
  11. Article
  12. Review
  13. Review
  14. Reduced CaFrontiers in neuroscience · 2022
    Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Reciprocal modulation of 5-HT and octopamine regulates pumping via feedforward and feedback circuits inProceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  20. Signal pathways involved in microbe-nematode interactions provide new insights into the biocontrol of plant-parasitic nematodes.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Sophie RengarajanDepartment of Microbiology, Immunology, and Molecular Genetics University of California, Los Angeles, Los Angeles, CA 90095, United States.
Elissa A HallemDepartment of Microbiology, Immunology, and Molecular Genetics University of California, Los Angeles, Los Angeles, CA 90095, United States. Electronic address: ehallem@ucla.edu.

Funding

UCLA-Caltech Medical Scientist Training ProgramT32GM008042 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI AJIJOLA, OLUJIMI A, DAWSON, DAVID WAYNE · 1985 to 2023
$29.9M
Training Program in Neural MicrocircuitsT32NS058280 · NINDS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI FELDMAN, JACK L · 2007 to 2017
$2.4M
The neural basis of odor-driven behavior in skin-penetrating parasitic nematodes.DP2DC014596 · NIDCD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI HALLEM, ELISSA ANYON · 2014 to 2014
$2.3M
Dopaminergic modulation of CO2 response during starvation in C. elegansF30GM116810 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI RENGARAJAN, SOPHIE · 2015 to 2017
$114k
NIDCD NIH HHS DP2 DC014596NIGMS NIH HHS F30 GM116810NIGMS NIH HHS T32 GM008042NINDS NIH HHS T32 NS058280
6 · The paper itself

Abstract

Over one billion people worldwide are infected with parasitic nematodes. Many parasitic nematodes actively search for hosts to infect using volatile chemical cues, so understanding the olfactory signals that drive host seeking may elucidate new pathways for preventing infections. The free-living nematode Caenorhabditis elegans is a powerful model for parasitic nematodes: because sensory neuroanatomy is conserved across nematode species, an understanding of the microcircuits that mediate olfaction in C. elegans may inform studies of olfaction in parasitic nematodes. Here we review circuit mechanisms that allow C. elegans to respond to odorants, gases, and pheromones. We also highlight work on the olfactory behaviors of parasitic nematodes that lays the groundwork for future studies of their olfactory microcircuits.

Indexed as

AnimalsBehavior, AnimalCaenorhabditis elegansChemotaxisNematodaOlfactory NerveSmell

Identifiers

PMID27668755
PMCPMC5123917

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.