ArticleEnvironmental science & technology2016
Conceptual Framework To Extend Life Cycle Assessment Using Near-Field Human Exposure Modeling and High-Throughput Tools for Chemicals.
Article in Environmental science & technology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
14 citing papers in PubMed.
- "If They Are Not Labeled, How Do We Know What's Risky and What's Not?": Assessing Information on Brominated Flame Retardants in Children's Plastic Products in South Africa.Environmental health insights · 2026Article
- Operationalization of the safe and sustainable by design framework for chemicals and materials: challenges and proposed actions.Integrated environmental assessment and management · 2025Article
- REACH assessment of humans exposed to chemicals indirectly via the environment: screening modeling in EUSES versus state of the science.Integrated environmental assessment and management · 2025Review
- Improving predictions of compound amenability for liquid chromatography-mass spectrometry to enhance non-targeted analysis.Analytical and bioanalytical chemistry · 2024Article
- Review of generic scenario environmental release and occupational exposure models used in chemical risk assessment.Journal of occupational and environmental hygiene · 2023Review
- Exposure Prioritization (Toxics · 2022Article
- Predicting compound amenability with liquid chromatography-mass spectrometry to improve non-targeted analysis.Analytical and bioanalytical chemistry · 2021Article
- Article
- Improving the reliability of chemical manufacturing life cycle inventory constructed using secondary data.Journal of industrial ecology · 2021Article
- Advances on a Decision Analytic Approach to Exposure-Based Chemical Prioritization.Risk analysis : an official publication of the Society for Risk Analysis · 2020Article
- Linking Molecular Structure via Functional Group to Chemical Literature for Establishing a Reaction Lineage for Application to Alternatives Assessment.ACS sustainable chemistry & engineering · 2019Article
- Applying Environmental Release Inventories and Indicators to the Evaluation of Chemical Manufacturing Processes in Early Stage Development.ACS sustainable chemistry & engineering · 2019Article
- A Model for Risk-Based Screening and Prioritization of Human Exposure to Chemicals from Near-Field Sources.Environmental science & technology · 2018Article
- Comparative, collaborative, and integrative risk governance for emerging technologies.Environment systems & decisions · 2018Article
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
Life Cycle Assessment (LCA) is a decision-making tool that accounts for multiple impacts across the life cycle of a product or service. This paper presents a conceptual framework to integrate human health impact assessment with risk screening approaches to extend LCA to include near-field chemical sources (e.g., those originating from consumer products and building materials) that have traditionally been excluded from LCA. A new generation of rapid human exposure modeling and high-throughput toxicity testing is transforming chemical risk prioritization and provides an opportunity for integration of screening-level risk assessment (RA) with LCA. The combined LCA and RA approach considers environmental impacts of products alongside risks to human health, which is consistent with regulatory frameworks addressing RA within a sustainability mindset. A case study is presented to juxtapose LCA and risk screening approaches for a chemical used in a consumer product. The case study demonstrates how these new risk screening tools can be used to inform toxicity impact estimates in LCA and highlights needs for future research. The framework provides a basis for developing tools and methods to support decision making on the use of chemicals in products.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.